Colitis cystica profunda mimicking mucinous adenocarcinoma of the rectum diagnosed by endoscopic submucosal dissection

Abstract

Video 1 Endoscopic submucosal dissection of colitis cystica profunda in the lower rectum along with resection of the tumor using the pocket-creation and clip-with-line methods. ▶ Fig. 3 The resected specimen. a Photograph of the resected specimen, approximately 9 × 6 cm in size. b Macroscopic view of the resected specimen, showing several cystic lesions containing mucin. c Histological images of the resected specimen stained with hematoxylin and eosin, showing colitis cystica profunda without findings of dysplasia or malignancy (× 12.5).

Colitis cystica profunda: A report of two cases

“…Conservative treatment is ineffective, and surgical resection is required when symptoms are persistent or severe, such as bowel obstruction, bleeding, or rectal prolapse 18,19 . In recent years, endoscopic submucosal dissection, with the advantages of rapid recovery, minimal trauma, and preservation of colonic integrity, has been widely used in treating CCP 20 …”

“…18,19 In recent years, endoscopic submucosal dissection, with the advantages of rapid recovery, minimal trauma, and preservation of colonic integrity, has been widely used in treating CCP. 20 In conclusion, CCP is a rare disease that is difficult to diagnose and easily misdiagnosed as other occupying lesions of the intestine because of its low incidence, lack of specificity in clinical and endoscopic manifestations, and lack of awareness among physicians in various disciplines. Once misdiagnosed, it brings unnecessary painful surgical resection to patients and poses risks to physicians.…”

“… 18 , 19 In recent years, endoscopic submucosal dissection, with the advantages of rapid recovery, minimal trauma, and preservation of colonic integrity, has been widely used in treating CCP. 20 …”

Colitis cystica profunda: a two-patient case series

“…Conservative treatment is ineffective and surgical resection is required when symptoms are persistent or severe, such as bowel obstruction, bleeding, or rectal prolapse [18,19] . In recent years, endoscopic submucosal dissection (ESD), with the advantages of rapid recovery, minimal trauma, and preservation of colonic integrity, has been widely used in the treatment of CCP [20] .…”

Colitis cystica profunda of the rectum diagnosed by endoscopic submucosal dissection

“…Treatment of CCP is mostly conservative and surgery is only suggested in patients with complications such as obstruction and bleeding. However, case reports recently showed that it not only mimicked well-differentiated rectal adenocarcinoma [3], but also accompanied by adenocarcinoma on the surface…”