Colistin Resistance among Enterobacterales Isolates: Underlying Mechanisms and Alternative Treatment Options
Amal F. Makled,
Sahar A.M. Ali,
Ahmed B. Mahmoud
et al.
Abstract:Global dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria (GNB) such as carbapenemase-producing Enterobacterales has resulted in reviving colistin as a final therapeutic alternative. Colistin resistance foretold a catastrophe. We aimed to detect the rates of carbapenems and colistin resistance among hospital-acquired Enterobacterales species, verify the underlying mechanisms and provide antibiogram for colistin-resistant isolates. The collected Enterobacteral… Show more
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