Colistin and tylosin enhances disaccharidase activities, and improves morphology and permeability of the intestine of broilers

Hung, Chuan-Chuan; Chen, C. Y.; Chen, Bao-Ji

doi:10.1080/00071668.2020.1747598

Cited by 7 publications

(7 citation statements)

References 33 publications

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“…Notably, the improved disaccharidases activities suggested that the utilization of intestinal nutrients in broiler chickens was strengthened, which probably promoted the improvement of growth performance in this study, that was in agreement with the outcomes of Wan et al. (2016) and Hung et al. (2020) .…”

Section: Disscusionsupporting

confidence: 87%

“…Thus, disaccharidases play crucial roles in digestion and absorption of carbohydrates. Sucrase, maltase, and isomaltase are 3 disaccharidases existed in the intestine of broiler chickens, which are the signs of intestinal functional maturation and also the key of final digestion ( Hung et al., 2020 ). In current study, dietary YC-EHY enhanced jejunal sucrase activity on 21 d of age as well as maltase activity on 21 and 42 d of age in broiler chickens, and the dosage of 100 mg/kg YC-EHY addition exhibited a better effect.…”

Section: Disscusionmentioning

confidence: 99%

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Effects of a yeast-derived product on growth performance, antioxidant capacity, and immune function of broilers

Wang

Cheng

et al. 2021

Poultry Science

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Yeast culture plus enzymatically hydrolyzed yeast cell wall ( YC-EHY ) contains crude protein, mannan-oligosaccharide, β-glucan and yeast culture. This study was carried out to explore the effects of dietary YC-EHY at different levels on growth performance, antioxidant capacity, and immune function of broiler chickens. A total of 320 one-day-age male broiler chicks were allocated into 4 groups and were fed with a basal diet supplemented with 0 mg/kg (the control group), 50 mg/kg, 100 mg/kg, 150 mg/kg YC-EHY for 42 d. Dietary YC-EHY improved average daily gain and feed efficiency during the starter, grower, and overall periods as well as average body weight of broiler chickens on 42 d (linear and quadratic, P < 0.05). Broiler chickens fed with YC-EHY quadratically increased jejunal sucrase activity on 21 d (quadratic, P < 0.05), and linearly and quadratically enhanced maltase activity on 21 and 42 d (linear and quadratic, P < 0.05). Supplementing YC-EHY linearly and quadratically enhanced jejunal superoxide dismutase ( SOD ) activity on 21 and 42 d and glutathione peroxidase ( GPX ) activity on 42 d whereas decreased malonaldehyde ( MDA ) concentration on 42 d (linear and quadratic, P < 0.05). Consistently, the jejunal genes expression of nuclear factor erythroid 2-related factor 2 ( Nrf2 ) and SOD1 on 21 and 42 d, heme oxygenase-1 ( HO-1 ) and GPX1 on 42 d were enhanced by YC-EHY supplementation (linear and quadratic, P < 0.05). The concentrations of jejunal immunoglobulin G ( IgG ) on 21 and 42 d and secreted immunoglobulin A ( SIgA ) on 42 d were linearly and quadratically elevated by supplementing YC-EHY (linear and quadratic, P < 0.05). Dietary YC-EHY quadratically increased jejunal IgG and IgM genes expression on 21 d (quadratic, P < 0.05), and linearly and quadratically enhanced the genes expression of IgG and IgM on 42 d (linear and quadratic, P < 0.05). Overall, this study indicated that supplementing YC-EHY could exert beneficial effects on growth performance, intestinal antioxidant capacity and immune function in broiler chickens.

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Section: Disscusionsupporting

confidence: 87%

Section: Disscusionmentioning

confidence: 99%

Effects of a yeast-derived product on growth performance, antioxidant capacity, and immune function of broilers

Wang

Cheng

et al. 2021

Poultry Science

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“…Tylosin is an antibiotic with beneficial effects on broiler performance. Hung et al [ 18 ] observed that the use of 55 mg/kg tylosin provided beneficial effects on digestion and intestinal integrity, increasing disaccharidase activity and maintaining intestinal permeability, consequently increasing performance.…”

Section: Discussionmentioning

confidence: 99%

Comparison of functional-oil blend and anticoccidial antibiotics effects on performance and microbiota of broiler chickens challenged by coccidiosis

et al. 2022

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This study aimed to compare the effects of different levels of cashew nutshell liquid (CNSL) and castor oil (CNSL–castor oil) with growth-promoting antibiotics associated with anticoccidials in broiler chickens challenged with coccidiosis. In this work, 2520 one-day-old male broiler chicks (Cobb) were randomly assigned to 84 pens, containing 30 birds each. The experimental design was completely randomized, with seven treatments: enramycin (8 ppm), virginiamycin (16.5 ppm), and tylosin (55 ppm); different doses of CNSL–castor oil (0.5, 0.75, and 1.00 kg/t); and a control diet (without additives). All treatments received semduramicin + nicarbazin (500 g/t; Aviax® Plus) from 0 to 28 d and monensin sodium (100 ppm; Elanco) from 29 to 35 days of age, when the feed was without antibiotics. The challenge was introduced at 14 days of age by inoculating broiler chickens with sporulated Eimeria tenella, Eimeria acervulina, and Eimeria maxima oocysts via oral gavage. In addition to performance parameters, intestinal contents were collected at 28 and 42 days of age for microbiota analysis by sequencing the 16s rRNA in V3 and V4 regions using the Illumina MiSeq platform. Taxonomy was assigned using the SILVA database (v. 138) with QIIME2 software (v. 2020.11). After one week of challenge, the broilers that received tylosin had a higher body weight gain (BWG) than those in the control group (p < 0.05), while the other treatments presented intermediate values. At 28 d, the BWG was lower for the control, CNSL–Castor oil 0.5 kg/t, enramycin, and virginiamycin treatments than that in the tylosin treatment. The inclusion of CNSL–Castor oil at concentrations of 0.75 and 1 kg/t acted as an intermediate treatment (p < 0.05). For alpha diversity, using the Shannon index, it was possible to observe the effect of age, with substantial diversity at 42 d. The Firmicutes phylum had the highest abundance, with values between 84.33% and 95.16% at 42 d. Tylosin showed better performance indices than other treatments. CNSL–castor oil treatments with concentrations of 0.75 and 1 kg/t showed similar results to those of enramycin and virginiamycin. Furthermore, CNSL–castor oil acted as a modulator of intestinal microbiota, reducing the abundance of pathogenic bacteria.

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“…Colistin is used as therapy, as protector, and even as a growth promoter especially in swine, in some countries [21,22]. The use of colistin and tyrosine as supplementation helped to the increase of body weight and the amount of feed intake in broilers [23]. Studies reporting colistin use from various countries demonstrated that China was the highest user of colistin in agriculture but in 2017, colistin was banned to be used as a growth factor for livestock [24].…”

Section: Introductionmentioning

confidence: 99%

Colistin Resistant mcr Genes Prevalence in Livestock Animals (Swine, Bovine, Poultry) from a Multinational Perspective. A Systematic Review

Valiakos

Kapna

2021

Veterinary Sciences

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The objective of this review is to collect and present the results of relevant studies on an international level, on the subject of colistin resistance due to mcr genes prevalence in livestock animals. After a literature search, and using PRISMA guidelines principles, a total of 40 swine, 16 bovine and 31 poultry studies were collected concerning mcr-1 gene; five swine, three bovine and three poultry studies referred to mcr-2 gene; eight swine, one bovine, two poultry studies were about mcr-3 gene; six swine, one bovine and one poultry manuscript studied mcr-4 gene; five swine manuscripts studied mcr-5 gene; one swine manuscript was about mcr-6, mcr-7, mcr-8, mcr-9 genes and one poultry study about mcr-10 gene was found. Information about colistin resistance in bacteria derived from animals and animal product foods is still considered limited and that should be continually enhanced; most of the information about clinical isolates are relative to enteropathogens Escherichia coli and Salmonella spp. This review demonstrates the widespread dispersion of mcr genes to livestock animals, indicating the need to further increase measures to control this important threat for public health issue.

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Colistin and tylosin enhances disaccharidase activities, and improves morphology and permeability of the intestine of broilers

Cited by 7 publications

References 33 publications

Effects of a yeast-derived product on growth performance, antioxidant capacity, and immune function of broilers

Effects of a yeast-derived product on growth performance, antioxidant capacity, and immune function of broilers

Comparison of functional-oil blend and anticoccidial antibiotics effects on performance and microbiota of broiler chickens challenged by coccidiosis

Colistin Resistant mcr Genes Prevalence in Livestock Animals (Swine, Bovine, Poultry) from a Multinational Perspective. A Systematic Review

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