Colic in two horses associated with smooth muscle intestinal tumours

Livesey, M. A.; Hulland, T. J.; Yovich, J. V.

doi:10.1111/j.2042-3306.1986.tb03645.x

Cited by 24 publications

(19 citation statements)

References 7 publications

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“…Colic has been previously described in horses with gastric SCC, 15,20,21,23 leiomyosarcoma, 6 and adenocarcinoma, 5 and may be because of pain associated with impaired gastric outflow and/or abdominal metastasis. Both horses in our study that were diagnosed with gastric leiomyoma had a history of recurrent colic, which is in agreement with previous reports of alimentary smooth‐muscle tumors causing abdominal pain 4,25,26 . Anxiety, abdominal pain, and anemia were the most likely causes of tachycardia in 37% of horses.…”

Section: Discussionsupporting

confidence: 91%

Gastric Neoplasia in Horses

Taylor

Haldorson

Vaughan

et al. 2009

Veterinary Internal Medicne

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Background: Gastric neoplasia of horses is incompletely described. Objective: Provide history, clinical signs, and clinicopathological and pathological findings associated with gastric neoplasia in horses. Animals: Twenty‐four horses with gastric neoplasia. Methods: Retrospective study. History, clinical signs, and clinicopathological and pathologic findings in horses diagnosed histologically with gastric neoplasia were reviewed. Results: Horses ranged in age from 9 to 25 years (median 18 years at presentation). There was no apparent breed or sex predisposition. The most common presenting complaints were inappetance (17/24), weight loss (14/24), lethargy (7/24), hypersalivation (7/24), colic (5/24), and fever (5/24). The most consistent clinical signs were tachypnea (10/19), decreased borborygmi (8/19), and low body weight (7/17). Useful diagnostic tests included rectal examination, routine blood analysis, gastroscopy, abdominocentesis, and transabdominal ultrasound examination. Anemia was the most common hematologic abnormality encountered (7/19), and hypercalcemia of malignancy was seen in 4/16 horses. Squamous cell carcinoma was the most common tumor identified (19/24), and was most often (14/19) found as a single ulcerated, necrotic mass in the nonglandular portion of the stomach. Other gastric neoplasms encountered were leiomyoma (n=2), mesothelioma (n=1), adenocarcinoma (n=1), and lymphoma (n=1). Metastatic neoplasia was found in 18/23 horses. The median time from onset of clinical signs to death was 4 weeks, and all horses died or were euthanized because of gastric neoplasia. Conclusions: Squamous cell carcinoma is the most common primary gastric neoplasia in horses. The survival time after diagnosis of gastric neoplasia in horses is short.

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Section: Discussionsupporting

confidence: 91%

Gastric Neoplasia in Horses

Taylor

Haldorson

Vaughan

et al. 2009

Veterinary Internal Medicne

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“…51 Three of 4 (75%) intestinal smooth-muscle neoplasms in this study involved the jejunum, which is consistent with cases reported in the literature. 10,52 Horses with smooth-muscle tumors typically demonstrate colic before diagnosis, which was observed in 75% of the horses diagnosed with leiomyosarcoma or leiomyoma in this study. 10,52 Whereas all horses with intestinal smooth-muscle neoplasms in the current study were euthanized, surgical resection is an option that may yield a favorable outcome because these tumors are often locally invasive, pedunculated, wellencapsulated, and extraluminal but do not typically metastasize to distant sites in horses.…”

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confidence: 91%

“…10,52 Horses with smooth-muscle tumors typically demonstrate colic before diagnosis, which was observed in 75% of the horses diagnosed with leiomyosarcoma or leiomyoma in this study. 10,52 Whereas all horses with intestinal smooth-muscle neoplasms in the current study were euthanized, surgical resection is an option that may yield a favorable outcome because these tumors are often locally invasive, pedunculated, wellencapsulated, and extraluminal but do not typically metastasize to distant sites in horses. 10,52 The small intestine was the most common location for intestinal neoplasia in this study, followed by large intestine and small colon.…”

mentioning

confidence: 91%

“…10,52 Whereas all horses with intestinal smooth-muscle neoplasms in the current study were euthanized, surgical resection is an option that may yield a favorable outcome because these tumors are often locally invasive, pedunculated, wellencapsulated, and extraluminal but do not typically metastasize to distant sites in horses. 10,52 The small intestine was the most common location for intestinal neoplasia in this study, followed by large intestine and small colon. Cecal neoplasia was present only in conjunction with adjacent segments of bowel.…”

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confidence: 99%

“…1 The alimentary form of lymphoma is the most common equine intestinal neoplasm, [1][2][3][4] and other intestinal neoplasms reported in horses include adenocarcinoma, [5][6][7][8][9] leiomyoma, leiomyosarcoma, 10 myxosarcoma, 11 ganglioneuroma, 12 nerve sheath tumor, 13 and carcinoid. 14 It is often a diagnostic challenge to differentiate intestinal neoplasia from inflammatory bowel disease, nonintestinal, intra-abdominal neoplasia, and internal abscessation, because patient history, clinical signs, and diagnostic results can be similar.…”

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confidence: 99%

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Intestinal Neoplasia in Horses

Taylor

Pusterla

Vaughan

et al. 2006

Veterinary Internal Medicne

102

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Background: Intestinal neoplasia of horses is inadequately described. Hypothesis: Intestinal neoplasia of horses has characteristic clinicopathologic features. Animals: Thirty-four horses with intestinal neoplasia. Methods: Retrospective study. Results: Anamnesis, clinical signs, clinicopathologic and pathologic findings in 34 adult horses diagnosed histologically with intestinal neoplasia were reviewed. The horses ranged in age from 2 to 30 years (mean 16.6 years at presentation). The Arabian breed was most represented and there was no sex predisposition. The most common presenting complaints were weight loss, colic, anorexia, and fever. The most consistent clinical signs were poor body condition, tachycardia, tachypnea, fever, and diarrhea. Useful diagnostic tools included rectal examination, routine blood analyses, abdominocentesis, ultrasonographic examination, rectal biopsy, and exploratory laparotomy. Alimentary lymphoma was the most common intestinal neoplasia identified, followed by adenocarcinoma and smooth muscle tumors. The small intestine was the most common segment of intestine affected for all neoplasms. Intestinal neoplasia was diagnosed antemortem in 13 of 34 (38%) horses. The median time from onset of clinical signs to death or euthanasia was 1.9 months. The discharge rate was 15%. Although the longest survival was observed in horses with jejunal adenocarcinoma, all horses were eventually euthanized because of intestinal neoplasia.Conclusions: Arabian horses were 4.5 times more likely to have intestinal neoplasia diagnosed than were other breeds.

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