Cold Stress and Hypoglycemia in the Late Preterm (“Near-Term”) Infant: Impact on Nursery of Admission

Laptook, Abbot R.; Jackson, Gregory L.

doi:10.1053/j.semperi.2006.01.014

Cited by 103 publications

(70 citation statements)

References 23 publications

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“…In a systematic review, Teune et al (25) have found a rate of 7.1% in late preterm infants. Laptook and Jackson (26) have stressed the increased incidence of nursery admissions in late preterem infants with hypoglycemia. In our study, hypoglycemia was twice as common in late preterm infants, which was comparable to the rates reported before (22,27).…”

Section: Discussionmentioning

confidence: 99%

Short-Term Outcomes and Mortality of Late Preterm Infants

2016

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Background: Late preterm infants have increased rates of morbidity and mortality compared to term infants. Determining the risk factors in these infants leads to more comprehensive preventive and treatment strategies. Aims: Our aim was to analyse the morbidity rates such as respiratory system diseases, infections, congenital anomalies, hypoglycemia and hematologic abnormalities and mortality rates in a large group of patients at a referral center. Study Design: Retrospective cross-sectional study. Methods: Medical records of late preterm and term infants who were managed at the referral center were analysed.Results: 41752 births were analysed in 3 years. 71.9% of all births were between 37-42 gestational weeks (i.e. term) and 16.1% were between 34-37 weeks (i.e. late preterm). Compared to term infants, late preterm infants had increased rates of short-term problems. The rate of mortality increased with decreased gestational age. The duration of hospitalization was significantly higher in the smallest late preterm infants. Conclusion: This study demonstrated the need that late preterm infants who have higher risk for morbidity and mortality, compared to term infants require close monitoring. The rate of mortality and hospitalization increased with decreased gestational age.

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Section: Discussionmentioning

confidence: 99%

Short-Term Outcomes and Mortality of Late Preterm Infants

2016

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“…4 In a population-based study, Moster et al 10 [12][13][14] Late preterm infants were repeatedly reported to have more complications and require more NICU admissions secondary to immaturity of their different systems. [15][16][17][18] Endotracheal intubation may or may not be associated with prolonged resuscitation as in many cases it can be related to the presence of meconium stained amniotic fluid. The impact of intubation alone may be hard to tease out especially with the flexibility given in NRP guidelines regarding the timing of the decision when to intubate.…”

Section: Discussionmentioning

confidence: 99%

Post-Resuscitation Care for Neonates Receiving Positive Pressure Ventilation at Birth

et al. 2014

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WHAT'S KNOWN ON THIS SUBJECT: Infants who require positive pressure ventilation at birth are considered to be at risk for subsequent compromise and are recommended to receive postresuscitation care. The supportive evidence and details of this care have not been fully investigated. WHAT THIS STUDY ADDS:We investigate the need for postresuscitation care in infants who require positive pressure ventilation at birth, review the aspects of care needed, and explore the important risk factors most predictive of it. METHODS: Our hospital admits any infant who requires PPV at birth to special (intermediate/intensive) neonatal care unit (SNCU) for observation for at least 6 hours. All infants $35 weeks' gestation born between 1994 and 2013, who received PPV at birth, were reviewed. We examined perinatal factors that could predict the need for PRC after short (,1 minute) and prolonged ($1 minute) PPV, admission course, neonatal morbidities, and the aspects of care given.RESULTS: Among 87 464 infants born, 3658 (4.2%) had PPV at birth with 3305 (90%) admitted for PRC. Of those, 1558 (42.6%) were in the short PPV group and 2100 (57.4%) in the prolonged PPV group. Approximately 59% of infants who received short PPV stayed in the SNCU for $1 day. Infants who received prolonged PPV were more likely to have morbidities and require special neonatal care. Multiple logistic regression analysis revealed the risk factors of placental abruption, assisted delivery, small-for-dates, gestational age ,37 weeks, low 5-minute Apgar score, and need for intubation at birth to be independent predictors for SNCU stay $1 day and need for assisted ventilation, central lines, and parenteral nutrition.

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“…In spite of plentiful research, the nadir glucose concentrations and the duration of HG that causes brain damage in new-borns are not adequately elucidated [1,3]. Moreover, the specific value of serum glucose for hypoglycaemia is not universally accepted [8][9][10][11][12]. The title "is the sixty the new forty" (mg/dl) is a striking example of the lack of solid evidence in defining the neonatal HG [13].…”

Section: Discussionmentioning

confidence: 99%

Hypoglycaemia in the Newborn

Stomnaroska

Petkovska

Ivanovska

et al. 2017

Prilozi

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aim: Severe neonatal hypoglycaemia (HG) leads to neurologic damage, mental retardation, epilepsy, impaired cardiac performance and muscle weakness. The aim was to assess the frequency and severity of HG in a population of newborns. Patients and methods:We investigated 739 patients with neonatal hypoglycaemia (HG) (M:F=370:369) born at the University Clinic for Gynaecology and Obstetritics in Skopje in the period 2014-2016 and treated at the neonatal intensive care unit (NICU). 1416 babies were treated in the same period in NICU, and HG was observed in 52.18%. The birth weight was dominated by children with low birth weight: very low birth weight (VLBW)(<1500g) 253 children, (34,23%), low birth weight (1500-2500g) 402 (54.39%), appropriate for gestational age (AGA) 78(10.55%), and high birth weight (>4000g) 6 babies (0.81%). The gestational age was also dominated by children with low gestational age: gestational week (GW) 20-25 four children (0.54%), 26-30 GW 133 babies (17.99%), 31-35 GW472 (63.87%), and 36-40 GW130 neonates (17.59 %). 241 mothers (32.61%) have had an infection during pregnancy, 82 preeclampsia or eclampsia (11.09%), 20 diabetes mellitus (2.70%), 78 placental situations (placenta previa, abruption) (10.55%). In this study 47 babies (6.35%) with HG and co-morbidities died. There was a significant positive correlation between HG birth weight (p<0.01), gestational age (p<0.05), and the lowest Apgar score (p<0.01). Neonatal deaths were significantly correlated with GA (р>0,01), co-morbidities of the mothers (р>0,05) but not with the birth weight (р>0,05). In contrast, a significant positive correlation was found between convulsions and body weight (р<0.05). The lowest Apgar score was positively correlated with the gestational age (0.01), but not with the birth weight (0.05). conclusion: Low birth weight, low gestational age, maternal risk factors, hypoxic-ischemic encephalopathy and neonatal infections are associated with HG and are a significant factor in overall neonatal mortality. Those results indicate that diminishing the frequency of the neonatal HG and the rates of neonatal mortality requires complex interaction of prenatal and postnatal interventions.

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Cold Stress and Hypoglycemia in the Late Preterm (“Near-Term”) Infant: Impact on Nursery of Admission

Cited by 103 publications

References 23 publications

Short-Term Outcomes and Mortality of Late Preterm Infants

Short-Term Outcomes and Mortality of Late Preterm Infants

Post-Resuscitation Care for Neonates Receiving Positive Pressure Ventilation at Birth

Hypoglycaemia in the Newborn

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