1945
DOI: 10.1172/jci101575
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Cold Hemagglutination and Cold Hemolysis. The Hemolysis Produced by Shaking Cold Agglutinated Erythrocytes

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Cited by 28 publications
(2 citation statements)
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“…They demonstrate, too, that massive autoagglutination for short periods '59 iri vitro (i.c., 15 minutes), on the other hand, docs not damage the crythrocytcs sufficiently to bring about their liacmolysis on subsequent reinjection into a patient. However, this docs not provc that autoagglutination iri vivo is not important, for as originally strcsscd by Stats (1945) agglutinated corpuscles arc certainly unusually scnsitive to Iysis by nicchanical trauma. Our prcsent cxpcrinicnts provide no cvidcncc as to the actual iniportancc of this mcchanisin irr v i m ; they do, howcvcr, sccm to point strongly to coinplenicnt adsorption as an iniportaiit alternative or additional nieclianisin of hacmolysis.…”
Section: Discussionmentioning
confidence: 85%
“…They demonstrate, too, that massive autoagglutination for short periods '59 iri vitro (i.c., 15 minutes), on the other hand, docs not damage the crythrocytcs sufficiently to bring about their liacmolysis on subsequent reinjection into a patient. However, this docs not provc that autoagglutination iri vivo is not important, for as originally strcsscd by Stats (1945) agglutinated corpuscles arc certainly unusually scnsitive to Iysis by nicchanical trauma. Our prcsent cxpcrinicnts provide no cvidcncc as to the actual iniportancc of this mcchanisin irr v i m ; they do, howcvcr, sccm to point strongly to coinplenicnt adsorption as an iniportaiit alternative or additional nieclianisin of hacmolysis.…”
Section: Discussionmentioning
confidence: 85%
“…In addition the change in the metabolism of the cells or the ion-exchange between the erythrocytes and the INilieri probably also has a certain effect. Although agglutinated cells are more liable to trauma (Stats, 1945),…”
Section: F Po-tun Fok and Helwiut Schiibothementioning
confidence: 99%