Cold Hands, Warm Feet: Sleep Deprivation Disrupts Thermoregulation and Its Association with Vigilance

Romeijn, Nico; Verweij, Ilse M; Koeleman, A.; Mooij, Adriana H.; Steimke, Rosa; Virkkala, Jussi; Werf, Ysbrand D. van der; Someren, Eus J.W. Van

doi:10.5665/sleep.2242

Cited by 31 publications

(25 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…the decrease in vigour, and the increases in depression, confusion, tension, anger, fatigue, total mood disturbance and irritability), are in accordance with several previous studies that reported higher fatigue (Drake et al., ; Scott, Mcnaughton, & Polman, ), anxiety (Pires, Bezerra, Tufik, & Andersen, ), depressive symptoms (Paterson et al., ; Scott et al., ) and confusion (Drake et al., ), as well as reduced vigour (Drake et al., ; Scott et al., ), happiness (Paterson et al., ) and activation (Paterson et al., ) after sleep deprivation. In the present study, participants also felt more hungry and cold after sleep deprivation, which could be interpreted in line with the increased appetite (Knutson, Spiegel, Penev, & Van Cauter, ) and altered thermoregulation (Romeijn et al., ) described previously.…”

Section: Discussionsupporting

confidence: 91%

“…activation (Paterson et al, 2011) after sleep deprivation. In the present study, participants also felt more hungry and cold after sleep deprivation, which could be interpreted in line with the increased appetite (Knutson, Spiegel, Penev, & Van Cauter, 2007) and altered thermoregulation (Romeijn et al, 2012) The current results indicate that older adults are showing a similar decline in positive affect after sleep deprivation to young adults, but they seem superior at regulating negative affect. This is particularly interesting as negative items on mood scales cannot merely be considered antonyms of positive items (Steptoe et al, 2015).…”

Section: Discussionsupporting

confidence: 81%

See 1 more Smart Citation

Mood impairment is stronger in young than in older adults after sleep deprivation

Schwarz

Axelsson

Gerhardsson

et al. 2018

Journal of Sleep Research

View full text Add to dashboard Cite

Sleep deprivation commonly impairs affective regulation and causes worse mood. However, the majority of previous research concerns young adults. Because susceptibility to sleep deprivation and emotion regulation change distinctively across adult age, we tested here the hypothesis that the effect of sleep deprivation on mood is stronger in young than in older adults. In an experimental design, young (18–30 years) and older adults (60–72 years) participated in either a sleep control (young, n = 63; older, n = 47) or a total sleep deprivation condition (young, n = 61; older, n = 47). Sleepiness, mood and common symptoms of sleep deprivation were measured using established questionnaires and ratings. Sleep‐deprived participants felt more sleepy, stressed and cold, and reported lower vigour and positive affect, regardless of age. All the other outcome measures (negative affect, depression, confusion, tension, anger, fatigue, total mood disturbance, hunger, cognitive attenuation, irritability) showed a weaker response to sleep deprivation in the older group, as indicated by age*sleep deprivation interactions (ps < 0.05). The results show that older adults are emotionally less affected by sleep deprivation than young adults. This tolerance was mainly related to an attenuated increase in negative mood. This could possibly be related to the well‐known positivity effect, which suggests that older adults prioritize regulating their emotions to optimize well‐being. The results also highlight that caution is warranted when generalizing results from sleep deprivation studies across the adult lifespan.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 81%

Mood impairment is stronger in young than in older adults after sleep deprivation

Schwarz

Axelsson

Gerhardsson

et al. 2018

Journal of Sleep Research

View full text Add to dashboard Cite

show abstract

“…We additionally demonstrated that the magnitude of change (increase) in desire for high calorie foods was positively correlated with the perceived subjective severity of sleep deprivation across participants (indexed in the measure of sleepiness). Therefore, our data provide indirect support linking the state of sleep deprivation, and the subjective severity of this state, to altered internal homeostasis following extended time awake, and is consistent with already established alterations in metabolism and temperature regulation following sleep loss 26,27 . This may reflect a progressive deterioration in the brain and body systems that regulate and maintain optimal energy balance, potentially reflected in the current study by increases in energy consumption through heightened desire for high calorie foods.…”

Section: Discussionsupporting

confidence: 86%

The impact of sleep deprivation on food desire in the human brain

2013

View full text Add to dashboard Cite

Epidemiological evidence supports a link between sleep loss and obesity. However, the detrimental impact of sleep deprivation on central brain mechanisms governing appetitive food desire remains unknown. Here we report that sleep deprivation significantly decreases activity in appetitive evaluation regions within the human frontal cortex and insula cortex during food desirability choices, combined with a converse amplification of activity within the amygdala. Moreover, this bi-directional change in the profile of brain activity is further associated with a significant increase in the desire for weight-gain promoting high-calorie foods following sleep deprivation, the extent of which is predicted by the subjective severity of sleep loss across participants. These findings provide an explanatory brain mechanism by which insufficient sleep may lead to the development/maintenance of obesity through diminished activity in higher-order cortical evaluation regions, combined with excess subcortical responsivity in the amygdala, resulting in selection of foods most capable of triggering weight-gain.

show abstract

“…Upper and lower extremities did not appear as different dimensions, suggesting that the experience of their temperatures is integrated, at least in normal everyday life conditions. Interestingly, whereas the physiological fluctuations and responses of upper and lower extremities may indeed be synchronized under normal conditions, a recent study showed that they may diverge under the extreme condition of maintaining wakefulness without any sleep for more than 24 hours 32 . The pool of questions of the ETSRS allows for a follow up on these findings.…”

Section: Discussionmentioning

confidence: 99%

“…Thirdly, daytime performance and nocturnal sleep as well as their associated electroencephalographic profiles, respond to natural fluctuations and induced small changes in skin temperature within the thermoneutral zone 30,31 . Moreover, this association is altered both after experimentally disrupted sleep 32 and in people suffering from insomnia 33,34 . Finally, people with insomnia have poor judgment of whether the temperature of the sleeping environment is comfortable, 9 which may involve a relatively low gray matter volume in the orbitofrontal cortex, 35-37 given its crucial role in hedonic evaluation including thermal comfort 38,39 .…”

Section: Introductionmentioning

confidence: 99%

The experienced temperature sensitivity and regulation survey

et al. 2015

View full text Add to dashboard Cite

Individuals differ in thermosensitivity, thermoregulation, and zones of thermoneutrality and thermal comfort. Whereas temperature sensing and -effectuating processes occur in part unconsciously and autonomic, awareness of temperature and thermal preferences can affect thermoregulatory behavior as well. Quantification of trait-like individual differences of thermal preferences and experienced temperature sensitivity and regulation is therefore relevant to obtain a complete understanding of human thermophysiology. Whereas several scales have been developed to assess instantaneous appreciation of heat and cold exposure, a comprehensive scale dedicated to assess subjectively experienced autonomic or behavioral thermoregulatory activity has been lacking so far. We constructed a survey that specifically approaches these domains from a trait-like perspective, sampled 240 volunteers across a wide age range, and analyzed the emergent component structure. Participants were asked to report their thermal experiences, captured in 102 questions, on a 7-point bi-directional Likert scale. In a second set of 32 questions, participants were asked to indicate the relative strength of experiences across different body locations. Principal component analyses extracted 21 meaningful dimensions, which were sensitive to sex-differences and age-related changes. The questions were also assessed in a matched sample of 240 people with probable insomnia to evaluate the sensitivity of these dimensions to detect group differences in a case-control design. The dimensions showed marked mean differences between cases and controls. The survey thus has discriminatory value. It can freely be used by anyone interested in studying individual or group differences in thermosensitivity and thermoregulation.

show abstract

Cold Hands, Warm Feet: Sleep Deprivation Disrupts Thermoregulation and Its Association with Vigilance

Cited by 31 publications

References 34 publications

Mood impairment is stronger in young than in older adults after sleep deprivation

Mood impairment is stronger in young than in older adults after sleep deprivation

The impact of sleep deprivation on food desire in the human brain

The experienced temperature sensitivity and regulation survey

Contact Info

Product

Resources

About