Cold Atmospheric Plasma: methods of production and application in dentistry and oncology

Hoffmann, Clotilde; Berganza, Carlos J; Zhang, Junyi

doi:10.1186/2045-9912-3-21

Cited by 307 publications

(223 citation statements)

References 122 publications

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“…As previously mentioned, CAP is also used for anticancer therapy [20][21][22][23]. Vitamin C has also been suggested to have adverse effects on cancer cells [28].…”

Section: Combining Vitamin C With Cold Atmospheric Plasmamentioning

confidence: 99%

“…Interestingly, CAP is also being studied in oncology to eradicate tumor cells. It has been demonstrated that cold plasma can induce necrosis, apoptosis and cell detachment by disrupting certain phases of tumor cell replication [20]. CAP effectiveness has been demonstrated against dozens of tumor cell lines and tumor types in vitro and in vivo, respectively [21].…”

mentioning

confidence: 99%

“…CAP effectiveness has been demonstrated against dozens of tumor cell lines and tumor types in vitro and in vivo, respectively [21]. The unfortunate limitation in the use of CAP against tumors is that a high dose CAP exposure can also harm healthy mammalian cells [20], hence the need for precise micro devices. The recent focus in CAPanticancer treatment has thus been on developing small scale and high precision devices (micro capillaries), which led to successful inhibition of tumors [22,23].…”

mentioning

confidence: 99%

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Combination of Cold Atmospheric Plasma and Vitamin C Effectively Disrupts Bacterial Biofilms

Pandit¹,

Mokkapati²,

Helgadottir³

et al. 2017

Clin Microbiol

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Cold atmospheric plasma (CAP) is increasingly used in medical applications for eradication of bacterial and tumor cells. CAP treatment devices, known as plasma jet pens, produce reactive oxygen and nitrogen species at atmospheric pressure and room temperature. The produced reactive species are concentrated in a small and precisely defined area, allowing for high precision medical treatments. CAP has been demonstrated as very effective against planktonic bacterial cells. Unfortunately, bacterial cells in biofilms are typically aggregated and protected by dense exopolymeric matrix, synthesized and secreted by the bacterial community. The main limitation in using CAP against bacterial biofilms is the thick protective matrix of extracellular polymers that shields bacterial cells within this complex architecture. CAP has also been shown to effectively eradicate tumor cells, but the main current limitation is the susceptibility of the surrounding healthy tissues to higher doses. We have recently demonstrated that vitamin C, a natural food supplement, can be used to destabilize bacterial biofilms and render them more susceptible to the CAP killing treatment. Here we discuss the possible impact that a pre-treatment with vitamin C could have on CAP applications in medicine. Specifically, we argue that vitamin C could enhance the effectiveness of CAP treatments against both the bacterial biofilms and some selected tumors.

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“…As previously mentioned, CAP is also used for anticancer therapy [20][21][22][23]. Vitamin C has also been suggested to have adverse effects on cancer cells [28].…”

Section: Combining Vitamin C With Cold Atmospheric Plasmamentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Combination of Cold Atmospheric Plasma and Vitamin C Effectively Disrupts Bacterial Biofilms

Pandit¹,

Mokkapati²,

Helgadottir³

et al. 2017

Clin Microbiol

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“…humidity, gas temperature and pressure. Exposure of the bacterial samples to the plasma glow is always more effective than exposure to plasma afterglow as in the plasma glow the short-living species as well as longliving species have a high probability to reach the treated sample [23].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Microbicidal Activity of Atmospheric Pressure Non- Thermal Plasma Against Planktonic and Biofilm Forms

Azim¹,

Sadeq²,

Shaer³

et al. 2016

J Med Microb Diagn

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“…NTP has electrons at a hotter temperature than the heavy particles that are at room temperature which are usually in helium, argon, nitrogen, helium and air. 14 The method of plasma treatment advances the surface adaptation of dental materials. 15 In the previous studies, it is reported that surface modification using plasma treatment have improved the bonding strength between heat cured acrylic resin and self-curing acrylic resin.…”

Section: 대한치과보철학회지 56권 3호 2018년 7월mentioning

confidence: 99%

Nonthermal plasma on the shear bond strength of relining resin to thermoplastic denture base resin

Manaloto-Ceballos

Labriaga

Song

et al. 2018

J Korean Acad Prosthodont

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3Denture base repair or relining is mandatory for the prolonged service life of the prosthesis. 9 The application of chairside autopolymerizing resins seems to have increased because direct relining is more convenient and faster than indirect laboratory processed relining. 3 However, thermoplastic denture base resins have high chemical resistance due to its high degree of crystallinity causing difflculty in the penetration of monomer molecules and other resin primers into https: //doi.org/10.4047/jkap.2018.56.3.199 Purpose: This study evaluated the effect of nonthermal plasma treatment on the bond strength of autopolymerizing relining resin to the injection molded thermoplastic denture base resins (TDBRs) with different surface treatments. Materials and methods: Acrylic Resin (Acrytone), Polyester (Estheshot-Bright), Polyamide (Valplast) and Polypropylene (Weldenz) were subjected to various surface treatments: No treatment, Nonthermal plasma, Sandblasting, Sandblasting and nonthermal plasma. Specimens were bonded using an autopolymerizing relining resin. Shear bond strength was tested using universal testing machine with crosshead speed of 1 mm/min. Statistical analysis by two-way analysis of variance with Tukey's test post hoc was used. Results: Acrytone showed significantly higher shear bond strength value among other TDBR group while Weldenz had the lowest. The sandblasting and nonthermal plasma condition had significantly higher shear bond strength value in all of the resin groups (P < .05). Conclusion:The use of nonthermal plasma treatment showed limited effect on the shear bond strength between TDBRs and relining resin, and combination of nonthermal plasma and sandblasting improved the shear bond strength between TDBR and reline material. (J Korean Acad Prosthodont 2018;56:199-205)

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Cold Atmospheric Plasma: methods of production and application in dentistry and oncology

Cited by 307 publications

References 122 publications

Combination of Cold Atmospheric Plasma and Vitamin C Effectively Disrupts Bacterial Biofilms

Combination of Cold Atmospheric Plasma and Vitamin C Effectively Disrupts Bacterial Biofilms

Assessment of Microbicidal Activity of Atmospheric Pressure Non- Thermal Plasma Against Planktonic and Biofilm Forms

Nonthermal plasma on the shear bond strength of relining resin to thermoplastic denture base resin

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