British Journal of Anaesthesia
 1976
DOI: 10.1093/bja/48.6.509
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Cold Adaptation and the Anaesthetic Requirement for Cyclopropane in Rats

John A. Reitan
1
,
S.T. Ainslie
2
,
Richard W. Martucci
3
et al.

Abstract: The effect of cold adaptation at 4 degrees C on cyclopropane MAC was studied in 10 Wistar rats over a 16-week period. Compared with a similar control group (normally adapted), there was a significant decrease in weight gain and a significant increase in anaesthetic requirement in the cold-adapted rats.

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