1988
DOI: 10.1016/0016-5085(88)90692-0
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Colchicine therapy of the renal amyloidosis of ulcerative colitis

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Cited by 39 publications
(13 citation statements)
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“…The sporadic cases of nephrotic syndrome due to secondary amyloidosis that resolved after prolonged treatment with colchicine have been recently described in association with FMF [35], inflammatory bowel disease [48], ankylosing spondylitis [49]and psoriatic arthritis [27]. Our case is an additional illustration of the success of colchicine treatment of nephrotic syndrome in a psoriatic patient with amyloidosis.…”
Section: Discussionmentioning
confidence: 68%
“…The sporadic cases of nephrotic syndrome due to secondary amyloidosis that resolved after prolonged treatment with colchicine have been recently described in association with FMF [35], inflammatory bowel disease [48], ankylosing spondylitis [49]and psoriatic arthritis [27]. Our case is an additional illustration of the success of colchicine treatment of nephrotic syndrome in a psoriatic patient with amyloidosis.…”
Section: Discussionmentioning
confidence: 68%
“…Besides the preventive and the curative effects of these drugs on amyloidosis-complicated familial Mediter ranean fever, a beneficial response was obtained in renal amyloidosis-complicated ulcerative colitis [11]. Although the response to colchicine in primary' amyloidosis is ques tionable and highly controversial, a favorable response was reported by Kyle et al [12] in patients with systemic primary amyloidosis and by Livingstone et al [ 13] in a patient with primary amyloidosis involving the urinary bladder.…”
Section: Discussionmentioning
confidence: 78%
“…In the glomeru li, amyloid fibrils were seen in the subendothelial and mesangial areas. Colchicine, which has a very long history in therapeu tics, has recently been reported to help in the prevention and treatment of amyloidosis related to familial Mediter ranean fever [10] and ulcerative colitis [11], The objective of this work was to study the possible preventive and cura tive effects of colchicine on experimentally (Schislosoma)-induced renal amyloidosis in Syrian golden hamsters.…”
Section: Introductionmentioning
confidence: 99%
“…Ermutigende Berichte finden sich über AA-Amyloidosen bei unterschiedlichen Grundkrankheiten. In zwei Berichten über Patienten mit Colitis ulcerosa war nach 0,6 bis 1,2mg Colchizin/d die Proteinurie von 9g/d auf 0,53g/d nach 8 Monaten und von 13,7g/d auf 0,37g/d nach 9 Jahren rückläufig (34). Die Inzidenz einer sekundären Amyloidose bei familiärem Mittelmeerfieber (29,33) durch prophylaktische Gabe von niedrig dosiertem Colchizin konnte von 30% unter 0,5% gesenkt werden.…”
Section: Colchizinunclassified