1998
DOI: 10.1016/s0140-6736(05)79420-4
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Colchicine in pyoderma gangrenosum

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Cited by 15 publications
(14 citation statements)
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“…Sulfones such as dapsone act by inhibiting neutrophils; they also appear to prevent edema and may decrease acute inflammatory reactions. 8,21 Rampal and associates 22 treated PG with associated inflammatory bowel disease with colchicine alone. Cyclosporin A is increasingly being used for patients in whom the disease is refractory to all other forms of treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Sulfones such as dapsone act by inhibiting neutrophils; they also appear to prevent edema and may decrease acute inflammatory reactions. 8,21 Rampal and associates 22 treated PG with associated inflammatory bowel disease with colchicine alone. Cyclosporin A is increasingly being used for patients in whom the disease is refractory to all other forms of treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Colchicine at Plastic and Reconstructive Surgery • February 2006 1 mg daily is reportedly effective for both the treatment and suppression of pyoderma gangrenosum recurrence, possibly related to interactions with the cytokine activity of lymphocytes and macrophages present in dermal lesions. 12 Systemic antibiotic therapy plays an important role. Many patients are first misdiagnosed with soft-tissue infections and then subsequently diagnosed with pyoderma gangrenosum after treatment with antibiotics has failed.…”
Section: Discussionmentioning
confidence: 99%
“…Dermatitis herpetiformis [26] Linear IgA disease [27] Epidermolysis bullosa acquisita [28] Chronic Bullous Dermatosis of Childhood [29] Vasculitis: Leucocytoclastic vasculitis (LCV) and Urticarial vasculitis [30] Scleroderma [31] Amyloidosis [32][33][34] Miscellaneous [35][36][37][38][39][40][41][42][43][44][45][46][47] phagocytosis, colchicine may increase superoxide scavenging activity of neutrophils which is impaired in this syndrome.…”
Section: Treatment Of Acute Gout and Familial Mediterranean Fevermentioning
confidence: 99%
“…[33] Oral colchicine is useful in the management of primary cutaneous amyloidosis. [34] Miscellaneous Colchicine was found to be effective in erythema nodosum leprosum, [35,36] pyoderma gangrenosum, [37] severe cystic acne, [38] calcinosis cutis, [39] keloids, sarcoid, condyloma acuminata, [40] fibromatosis, [41] relapsing polychondritis, [42] primary anetoderma, [43] subcorneal pustular dermatosis, [44] erythema nodosum, [45] scleredema, [46] and actinic keratosis. [47] …”
Section: Amyloidosismentioning
confidence: 99%