Coining attributes of ultra-low concentration graphene oxide and spermine: An approach for high strength, anti-microbial and osteoconductive nanohybrid scaffold for bone tissue regeneration

Ghorai, Sanjoy Kumar; Maji, Somnath; Subramanian, Bhuvaneshwaran; Maiti, Tapas K.; Chattopadhyay, Santanu

doi:10.1016/j.carbon.2018.09.062

Cited by 23 publications

(30 citation statements)

References 76 publications

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“…These unique properties of graphene and its derivatives have made these nanostructured materials suitable for various biological and medical applications [168] including anti-pathogenic applications [169] , [170] , [171] , [172] , [173] , [174] , [175] , [176] , [177] , biosensors [178] , [179] , [180] , [181] , [182] , [183] , [184] , bioimaging [185] , [186] , [187] , [188] , [189] , [190] , [191] , [192] , tissue engineering [193] , [194] , [195] , [196] , drug delivery [197] , [198] , [199] , [200] , [201] . Therefore, the interactions between graphene materials and viruses should be of great interest.…”

Section: Graphene-based Materialsmentioning

confidence: 99%

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Seifi

Kamali

2021

Medicine in Drug Discovery

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Coronavirus disease-2019 has been one of the most challenging global epidemics of modern times with a large number of casualties combined with economic hardships across the world. Considering that there is still no definitive cure for the recent viral crisis, this article provides a review of nanomaterials with antiviral activity, with an emphasis on graphene and its derivatives, including graphene oxide, reduced graphene oxide and graphene quantum dots. The possible interactions between surfaces of such nanostructured materials with coronaviruses are discussed. The antiviral mechanisms of graphene materials can be related to events such as the inactivation of virus and/or the host cell receptor, electrostatic trapping and physico-chemical destruction of viral species. These effects can be enhanced by functionalization and/or decoration of carbons with species that enhances graphene-virus interactions. The low-cost and large-scale preparation of graphene materials with enhanced antiviral performances is an interesting research-direction to be explored.

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Section: Graphene-based Materialsmentioning

confidence: 99%

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Seifi

Kamali

2021

Medicine in Drug Discovery

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“…Previous reports have demonstrated that the abundant mineralization related groups (epoxide, and carboxylic groups) on GO surface can act as effective nucleation sites for precipitating Ca 2+ , and then regulate the nucleation and growth process of HAP nanocrystals [21] , [22] . The HAP nanocrystals can form tight interfacial bonding with GO nanosheets and distribute homogeneously on the surface of GO nanosheets thus avoiding their aggregation [23] , [24] , [25] .…”

Section: Introductionmentioning

confidence: 99%

In situ synthesis of hydroxyapatite nanorods on graphene oxide nanosheets and their reinforcement in biopolymer scaffold

Shuai

Peng

Feng

et al. 2022

Journal of Advanced Research

151

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“…In response, many synthetic biocompatible materials have been developed and used in bone tissue engineering. However, most biocompatible materials are insufficient in their mechanical properties 4 , lack bioactivity, have uncontrolled degradation rates 5 , and thus, cannot help with native bone regeneration for certain physiological conditions 6 . Therefore, developing biocompatible materials with superior mechanical properties and osteogenic bioactivity has attracted significant attention in the field of bone tissue regeneration 7,8 .…”

Section: Introductionmentioning

confidence: 99%

Synthesis of high-quality monolayer tungsten disulfide with chlorophylls and its application for enhancing bone regeneration

et al. 2020

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Due to the population explosion of the 21st century, nearly one billion people are over 64 years of age and bone fracture is one of the most frequent problems facing both sexes because of osteoporosis. However, difficulty in enhancing bone regeneration to repair bone fracture poses challenges and thus, a two-dimensional monolayer material (i.e. tungsten disulfide (WS2)) could be one of the candidates offering a possible solution to the problem. Here, we prepare high-quality monolayer WS2 thin sheets in a large quantity with the assistance of extracted chlorophyll molecules, the natural pigment used in photosynthesis, via a liquid-phase exfoliation method. Then, the exfoliated WS2 sheets were mixed with polycaprolactone (PCL)/calcium silicate (CS) to form a biocompatible WS2-based composite. The in vivo experiments show that the bone regeneration of the WS2-based composite was 120% superior to commercially available mineral trioxide aggregate (MTA) bone cement. Moreover, the mechanical properties of the WS2-based composite exhibited ~300% enhancement over PCL/CS, which is one of the most commonly used bone regeneration materials. Our findings highlight the prospects for the composite of WS2 towards the improvement of bone regeneration applications.

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Coining attributes of ultra-low concentration graphene oxide and spermine: An approach for high strength, anti-microbial and osteoconductive nanohybrid scaffold for bone tissue regeneration

Cited by 23 publications

References 76 publications

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

In situ synthesis of hydroxyapatite nanorods on graphene oxide nanosheets and their reinforcement in biopolymer scaffold

Synthesis of high-quality monolayer tungsten disulfide with chlorophylls and its application for enhancing bone regeneration

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