Coincidence of obesity associated with cardio-renal abnormalities in Thais obese population

Dansethakul, Prabhop; Chuedoung, Arunsri; Worachartcheewan, Apilak; Panichanapan, Pradit; Pidetcha, Phannee

doi:10.1016/j.dsx.2015.09.018

Cited by 1 publication

(1 citation statement)

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“…Obesity is a body fat excess as a result of positive energy balance or it is an excess of body fat mass that linked with frequent metabolic disorders such as ischemic heart diseases, dyslipidemia, type 2 diabetes mellitus, and hypertension [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients

Al-Kuraishy¹,

Al-Gareeb²

2016

J Intercult Ethnopharmacol

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Aim:The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients.Patients and Methods:A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated with G. cambogia 166 mg/day, and third group treated with orlistat 120 mg/day plus G. cambogia 166 mg/day. The duration of the treatments was three consecutive months. Body mass index (BMI), VAI, blood pressure, blood glucose, total lipid profile, atherogenic index, and cardiac risk ratio were recorded at baseline and after 3 months.Results:The treatment with G. cambogia leads to reduction in VAI P < 0.05, whereas orlistat has a beneficial effect on cardiometabolic profiles without a reduction in VAI P > 0.05. Combined therapy of G. cambogia plus orlistat showed the more significant effect in reduction of VAI P < 0.05, cardiometabolic profiles and anthropometric measures P < 0.01 compared to pretreatment period.Conclusion:Combination of G. cambogia with orlistat lead to more significant effect than orlistat alone in amelioration of cardiometabolic profile and VAI in obese patients.

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Section: Introductionmentioning

confidence: 99%