Cohort Profile: The Amirkola Health and Ageing Project (AHAP)

Hosseini, Seyed Reza; Cumming, Robert G.; Kheirkhah, Farzan; Nooreddini, Hajighorban; Baiani, Mohammadali; Mikaniki, Ebrahim; Taghipour, Morteza; Akhavan‐Niaki, Haleh; Rasoulinejad, Seyed Ahmad; Mostafazadeh, Amrollah; Parsian, Hadi; Bijani, Ali

doi:10.1093/ije/dyt089

Cited by 51 publications

(46 citation statements)

References 16 publications

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“…It is part of a large cohort study known as the "Amirkola Health and Ageing Project" (AHAP) (20). The Medical ethics committee of Babol University of Medical Sciences approved the project.…”

Section: Methodsmentioning

confidence: 99%

The Association Between Zinc and Cognitive Impairment in Elderly People of Iran

et al. 2017

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Section: Methodsmentioning

confidence: 99%

The Association Between Zinc and Cognitive Impairment in Elderly People of Iran

et al. 2017

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“…Since 2011, it has been started and has continued so far. A total of 1616 people, who were 60 years old or more, were entered into the study (response rate = %72) (22). The study protocol was approved by the research council of the Babol University of Medical Sciences (number 2736).…”

Section: Methodsmentioning

confidence: 99%

The Prevalence of Self-Reported Sleep Problems and Some Factors Affecting It Among the Elderly in Amirkola

et al. 2017

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Background: Knowing the quality of sleep in the elderly and its effective factors helps to take measures in increasing or decreasing their effect. Objectives: The aim of this study is to determine the sleep problems and its effective factors in the elderly of Amirkola, the northern part of Iran. Methods: This cross-sectional study was extracted from the Amirkola health and ageing project (AHAP), which is a cohort project regarding the elderly in the city of Amirkola, the northern part of Iran. Since 2011, it has been started and has continued so far. Data including age, sex, level of education, life status, occupation, smoking, physical activity, self-reported chronic diseases, depressive symptoms by Geriatric depression scale (GDS), cognitive status by mini-mental state examination (MMSE), history of medication, and questions regarding sleep problems were collected by interviewing with older people or their close relatives. Results: The overall prevalence of sleep disorders in this study was 354 (24.8%). Gender, drug use, marital status, chronic pain, depression, urinary incontinence, education level, metabolic syndrome, occupation, MMSE, hypnotics, and diabetes were associated with the prevalence of sleep disorders. According to the logistic regression analyses, 12-month back pain (OR = 1.64, P = 0.003), hypnotic drugs (OR = 1.5, P = 0.03), depression (OR = 1.66, P = 0.001), age range of 75 to 79 years old (OR = 0.58, P = 0.01), accompanying chronic disease (OR = 1.15, P < 0.001), and MMSE (OR = 1.59, P = 0.003) had a significant role in sleep problems. Conclusions: This study showed a high prevalence of sleep disorders in the elderly in Amirkola, especially in women. It is necessary to assess all older individuals with sleep disorders for identifying and treatment risk factors.

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“…The population of this study was elderly persons from Amirkola Health and Aging Project (AHAP) [22] in which people aged ≥60 years old were recruited for health study. According to the AHAP study, written informed consent was obtained after the oral explanation of the study.…”

Section: Study Populationmentioning

confidence: 99%

Homocysteine, trace elements and oxidant/antioxidant status in mild cognitively impaired elderly persons: a cross-sectional study

Negahdar

Hosseini

Parsian

et al. 2015

Romanian Journal of Internal Medicine

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Introduction. Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD), so identification of the related risk factors can be helpful. There are controversial data regarding the serum oxidant/antioxidant status, trace elements and homocysteine (Hcy) as effective parameters in this disease, therefore the status of these factors was determined in this study.Methods. One hundred-twenty elderly persons with cognitive impairment and 120 elderly healthy persons who were differentiated using Mini-mental state examination (MMSE) participated in this study. The patients were divided into mild and moderate-to-severe cognitive impairment group. Serum antioxidant/oxidant, copper (Cu), manganese (Mn), zinc (Zn) and Hcy concentrations were measured using routine methods.Results. Oxidant and antioxidant levels increased and decreased based on the severity of the disease and were higher and lower in patients than in control group, respectively (p<0.001). With adjusting for age, gender and education, significant difference in Hcy levels was not observed. There was no significant difference in trace elements levels among groups.Conclusions. Results confirmed the association between oxidative damage with increasing the severity of cognitive impairment. These factors may be involved in the etiology of cognitive impairment and AD. Identification of such biomarkers is important to select appropriate treatment goals before the onset of irreversible clinical signs.

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Cohort Profile: The Amirkola Health and Ageing Project (AHAP)

Cited by 51 publications

References 16 publications

The Association Between Zinc and Cognitive Impairment in Elderly People of Iran

The Association Between Zinc and Cognitive Impairment in Elderly People of Iran

The Prevalence of Self-Reported Sleep Problems and Some Factors Affecting It Among the Elderly in Amirkola

Homocysteine, trace elements and oxidant/antioxidant status in mild cognitively impaired elderly persons: a cross-sectional study

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