Cohort mortality study of Philadelphia firefighters

Baris, Dalsu; Garrity, Thomas J.; Telles, Joel Leon; Heineman, Ellen F.; Olshan, Andrew F.; Zahm, Shelia Hoar

doi:10.1002/ajim.1040

Cited by 113 publications

(95 citation statements)

References 27 publications

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“…In a later proportionate mortality study, Watanabe and Kang 262 reported similar findings for army (PMR 5 0.87, 95% CI: 0.61-1.20) and marine (PMR 5 0.51, 95% CI: 0.14-1.31) Vietnam veterans. Cancer incidence and mortality studies of firefighters reported excess risks for multiple myeloma 116,[263][264][265] however, the specific exposures likely to drive these associations we are not indicated.…”

Section: Other Occupational and Environmental Factorsmentioning

confidence: 87%

Multiple myeloma: A review of the epidemiologic literature

et al. 2007

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Multiple myeloma, a neoplasm of plasma cells, accounts for 15% of lymphatohematopoietic cancers (LHC) and 2% of all cancers in the US. Incidence rates increase with age, particularly after age 40, and are higher in men, particularly African American men. The etiology is unknown with no established lifestyle, occupational or environmental risk factors. Although several factors have been implicated as potentially etiologic, findings are inconsistent. We reviewed epidemiologic studies that evaluated lifestyle, dietary, occupational and environmental factors; immune function, family history and genetic factors; and the hypothesized precursor, monoclonal gammopathies of undetermined significance (MGUS). Because multiple myeloma is an uncommon disease, etiologic assessments can be difficult because of small numbers of cases in occupational cohort studies, and few subjects reporting exposure to specific agents in case-control studies. Elevated risks have been reported consistently among persons with a positive family history of LHC. A few studies have reported a relationship between obesity and multiple myeloma, and this may be a promising area of research. Factors underlying higher incidence rates of multiple myeloma in African Americans are not understood. The progression from MGUS to multiple myeloma has been reported in several studies; however, there are no established risk factors for MGUS. To improve our understanding of the causes of multiple myeloma, future research efforts should seek the causes of MGUS. More research is also needed on the genetic factors of multiple myeloma, given the strong familial clustering of the disease. ' 2007 Wiley-Liss, Inc.Key words: multiple myeloma; epidemiology Multiple myeloma is a malignancy of plasma cells that results in an overproduction of light and heavy chain monoclonal immunoglobulins. The specific immunoglobulin secreted by the malignant cell is the M-protein, named in reference to its monoclonal characteristics. It is found in the serum and/or urine of persons affected with multiple myeloma.

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Section: Other Occupational and Environmental Factorsmentioning

confidence: 87%

Multiple myeloma: A review of the epidemiologic literature

et al. 2007

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“…However, international research conducted on this occupation showed that the suicide risk for fire fighters is actually lower than the general male population. 35,36 Only four suicide-prevention programs targeted people from culturally and linguistically diverse backgrounds. Migration has been considered a potential factor of stress, which may trigger mental health problems and suicidal behaviours.…”

Section: Discussionmentioning

confidence: 99%

Review of suicide-prevention programs in Queensland: state- and community-level activities

Arnautovska¹,

Kõlves²,

Ide³

et al. 2013

Aust. Health Review

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Objective. Information regarding the availability of suicide-prevention programs in Australia is sparse and rather difficult to obtain. This study aimed to report and describe suicide and/or self-harm-prevention programs in Queensland.Methods. Programs were classified by type of intervention, predominant type of program, setting of delivery and targeted population-at-risk.Results. Sixty-six organisations were identified, providing a total of 101 suicide-prevention programs. The majority of programs operated at the prevention or treatment level, with less than half providing continuing (long-term) care. The programs targeted 12 different risk groups and were most frequently delivered within community settings.Conclusions. The findings show a diverse distribution of activities across the levels of prevention and different risk populations. This survey demonstrates the existence of remarkable gaps in coverage and provision of programs for specific high-risk groups.What is known about the topic? Although suicide prevention in Australia has recently received considerable attention, there is currently no complete list or register of suicide-prevention programs. This reduces the opportunity for people at risk to access help, as well as agencies to link and build on existing models of service. What does this paper add? This study is unique in identifying and reviewing suicide-prevention programs that are funded by national or state suicide-prevention strategies, as well as those funded by private and community-based organisations. The identified programs are matched with the actual suicide risk of the targeted subpopulations, indicating a lack or overlap of programs for specific populations. What are the implications for practitioners? This paper is particularly relevant for policy makers as it identifies potential gaps in the provision of suicide-prevention programs for specific at-risk populations in Queensland. The relevance of the paper for practitioners, however, is in encouraging them to re-examine the provision of their services considering the entire continuum of suicide-prevention activities.

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“…For instance, Hanson 1990 [5] suggested an association between firefighters and lung cancer, but it is a singular finding among 12 other studies that find no increase in risk for lung cancer among firefighters [6]- [17]. Another occupational group that may have substantive PAH exposure is asphalt laying workers.…”

mentioning

confidence: 93%

Comparison of Urinary PAHs among Firefighters and Asphalt Pavers

Aquino

2017

ODEM

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Objective: The purpose of the investigation is to examine urinary biomarkers of polycyclic aromatic hydrocarbon (PAH) exposure among firefighters and asphalt workers. Methods: Average concentrations of urinary PAHs were used for comparative analysis between groups of firefighters and asphalt pavers. Microsoft Excel was used to perform calculations and the t-test was utilized for statistical analysis. Results: When compared to the National Institute of Standards and Technology (NIST) standard for smokers and non-smokers, firefighters demonstrated various statistically significant differences in urinary PAH concentrations. Asphalt workers had statistically significant higher urinary concentrations in three PAHs as compared to the NIST smoker mean. Conclusions: Firefighters did not demonstrate a substantial change in urinary PAH metabolite levels when compared to controls. Asphalt pavers experienced concentrations that were in some cases increased by orders of magnitude compared to controls.

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Cohort mortality study of Philadelphia firefighters

Cited by 113 publications

References 27 publications

Multiple myeloma: A review of the epidemiologic literature

Multiple myeloma: A review of the epidemiologic literature

Review of suicide-prevention programs in Queensland: state- and community-level activities

Comparison of Urinary PAHs among Firefighters and Asphalt Pavers

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