In this paper we study the cohomology of the geometric realization of linking systems with twisted coefficients. More precisely, given a prime p and a p-local finite group (S, F , L), we compare the cohomology of L with twisted coefficients with the submodule of F c -stable elements in the cohomology of S. We start with the particular case of constrained fusion systems. Then, we study the case of p-solvable actions on the coefficients.