Cognitive therapy for people with a schizophrenia spectrum diagnosis not taking antipsychotic medication: an exploratory trial

Morrison, Anthony P.; Hutton, Paul; Wardle, Melissa; Spencer, Helen; Barratt, Sarah; Brabban, Alison; Callcott, Pauline; Christodoulides, Thomas; Dudley, Robert; French, Paul; Lumley, Victoria; Tai, Sara; Turkington, Douglas

doi:10.1017/s0033291711001899

Cited by 62 publications

(38 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In later phases of illness, they are used as adjuncts to pharmacological treatments rather as standalone treatments. However, recent evidence suggests that some psychological treatments such as cognitive behavioural therapy (CBT) may be effective on their own 34,35 . A range of psychological therapies have been developed over the years of which CBT and family interventions have been recommended in clinical guidelines for early schizophrenia 36 .…”

Section: Psychological Therapiesmentioning

confidence: 99%

Conventional and alternative preventive treatments in the first stages of schizophrenia

et al. 2015

View full text Add to dashboard Cite

AUSTRALIAABSTRACT -Background and Objectives: Schizophrenia is a progressive disorder that moves through multiple stages starting from non-specific risk factors to at-risk mental state (ARMS) (also known as ultra-high risk of psychosis or UHR) to first episode of psychosis (FEP) to chronic course marred by frequent relapses and varying degrees of disability. In order to prevent a deteriorating course, treatments designed to address and possibly even correct the abnormal neuronal system functioning and psychosocial deficits need to be implemented early before potentially irreversible and maladaptive changes take place.Methods: A literature search was conducted in the electronic databases Pub-Med and MEDLINE for relevant empirical and review articles published in peer reviewed journals.Results: The review of literature suggests that a range of pharmacological and psychosocial interventions are being used and trialled in treatment of early stages of schizophrenia with varying degrees of success.Conclusions: There is a variety of therapies for schizophrenia ranging in scope from improving symptom profiles to functional recovery and a good rationale for their use early in the course of illness. Treatments that focus on integrating pharmacological, psychological and psychosocial interventions with a strong evidence base for effectiveness need to be integrated for the best chance to avert or hinder schizophrenia. Schizophrenia research is moving towards a notion that early intervention can interact with existing and intact neuroplasticity mechanisms that can be harnessed in an adaptive manner to promote healthier neural system functioning and increased stress resiliency, which will in turn lead to symptom reduction and functional recovery.

show abstract

Section: Psychological Therapiesmentioning

confidence: 99%

Conventional and alternative preventive treatments in the first stages of schizophrenia

et al. 2015

View full text Add to dashboard Cite

show abstract

“…35 The dominance of antipsychotic treatments as the automatic first-line approach could also be challenged. 36,37 A patient-centred choice would include being offered a full menu of evidence-based treatments as well as medication, such as psychological and family interventions. Patients and their families require clear and consistent information to be able to understand and weigh up the benefits and risks of antipsychotic medication, emphasising the trade-offs of improved mental health symptoms v. increased risks to physical health.…”

Section: Possibility Testmentioning

confidence: 99%

The cardiovascular health of young people with severe mental illness: addressing an epidemic within an epidemic

et al. 2012

View full text Add to dashboard Cite

SummaryFor young people with emerging psychosis, early weight gain and its potential cardiac and metabolic consequences amplify worrying UK public health trends for young people in general. This paper will argue that if clinicians dismiss these changes as of secondary concern in psychiatric treatment for their young patients, they may be inadvertently condoning a first critical step on a path towards physical health inequalities. Greater recognition is needed for this patient population in their 20s and 30s, at ages not normally considered for active primary or secondary cardiovascular prevention, who are at high risk of dying prematurely. The early phase of psychosis presents an important treatment window for protecting cardiometabolic health.

show abstract

“…Pharmacological treatment is limited in improving clinical, personal and social functioning and patients often have a high risk of relapse (Freeman et al 1998;A. K. Morrison 2009;A. P. Morrison et al 2011;Rathod et al 2008;Tarrier et al 2004).…”

Section: Introductionmentioning

confidence: 99%

Cognitive–behavioural therapy for patients with schizophrenia: a multicentre randomized controlled trial in Beijing, China

Guo

Wang

et al. 2014

Psychol. Med.

Self Cite

View full text Add to dashboard Cite

show abstract

Cognitive therapy for people with a schizophrenia spectrum diagnosis not taking antipsychotic medication: an exploratory trial

Abstract: This study provides preliminary evidence that CT is an acceptable and effective treatment for people with psychosis who choose not to take antipsychotic medication. An adequately powered randomized controlled trial is warranted.

Cited by 62 publications

References 34 publications

Conventional and alternative preventive treatments in the first stages of schizophrenia

Conventional and alternative preventive treatments in the first stages of schizophrenia

The cardiovascular health of young people with severe mental illness: addressing an epidemic within an epidemic

Cognitive–behavioural therapy for patients with schizophrenia: a multicentre randomized controlled trial in Beijing, China

Contact Info

Product

Resources

About