Cognitive retraining for organizational impairment in obsessive–compulsive disorder

Objectives: It is hypothesised that Weak Central Coherence (superior attention to detail with poorer bigger picture thinking) is a possible endophenotype for Anorexia Nervosa (AN). Currently the neuropsychological profile of children and adolescents with AN in unclear. The present review aimed to summarise the available literature with regards to the central coherence abilities of children and adolescents with AN, and clarify their neuropsychological profile.Method: The search found seven eligible studies. Meta-analyses were not possible due the variation in tasks used.Results: Evidence of less efficient global processing in children with AN was observed in a number of studies. The strongest evidence was observed from studies using the Rey Osterrieth Complex Figures Test (ROCFT). A visual comparison of ROCFT from child and adult AN studies highlighted similarities in global processing profiles. Conclusions:Evidence of inefficient global processing was observed across a number of studies. However methodological flaws in the current literature were highlighted and made interpretation difficult. These are discussed and recommendations for future research are made.

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“…Rey-Osterrieth Complex Figure Test (ROFT; [12]). The ROCFT was used in 6 studies [21,22,24,[26][27][28].…”

Section: Synthesis Of Resultsmentioning

confidence: 99%

A Systematic Review of Central Coherence in Young People with Anorexia Nervosa

Lang

Tchanturia

2014

J Child Adolesc Behav

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“…If executive functioning deficits can be identified as at least partial explanations for some of the OC symptoms in AN, cognitive behavioral interventions may be developed to specifically target these deficits. Preliminary studies have documented that OCD patients improve significantly in strategic verbal 54 and nonverbal 55 memory performance after simple instructional cueing. Further, gaining an understanding of the neural mechanisms underlying AN may also guide pharmacotherapy for these disorders.…”

Section: Resultsmentioning

confidence: 99%

Strategic memory in adults with anorexia nervosa: Are there similarities to obsessive compulsive spectrum disorders?

Sherman¹,

Savage²,

Eddy³

et al. 2006

Intl J Eating Disorders

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“…A recent meta-analysis demonstrated that CRT has a small to moderate effect on cognitive functioning following treatment and at follow-up assessments in individuals with schizophrenia [15]. Similar neurocognitive training modules have been developed in other areas, such as bipolar disorder [16] and obsessive-compulsive disorder [17]. Tchanturia and Davies [18] adapted and tailored CRT for eating disorders.…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Cognitive Remediation Therapy in Patients with a Severe or Enduring Eating Disorder: A Randomized Controlled Trial

Dingemans¹,

Danner

Donker³

et al. 2013

Psychother Psychosom

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Background: Individuals with eating disorders show deficits in neuropsychological functioning which might preexist and underlie the etiology of the eating disorders and influence relapse. Deficits in cognitive flexibility, i.e. set-shifting and central coherence, might perpetuate the symptoms. Cognitive remediation therapy (CRT) was developed to improve cognitive flexibility, thereby increasing the likelihood of improved outcome. The focus of CRT is on how patients think, rather than on what patients think. The present study investigated the effectiveness of CRT for patients with a severe or enduring eating disorder by means of a randomized controlled trial comparing intensive treatment as usual (TAU) to CRT plus TAU. Methods: Eighty-two patients were randomly assigned to CRT plus TAU (n = 41) or TAU alone (n = 41). Outcome measures were set-shifting, central coherence, eating disorder and general psychopathology, motivation, quality of life and self-esteem. Assessments were performed at baseline (n = 82) and after 6 weeks (T1; n = 75) and 6 months (T2; n = 67). Data were analyzed by means of linear mixed model analyses. Results: Patients who received CRT in addition to TAU improved significantly more with regard to eating disorder-related quality of life at the end of treatment (T1) and eating disorder psychopathology at follow-up (T2), compared to those who received TAU only. Moreover, moderator analyses revealed that patients with poor baseline set-shifting abilities benefited more from CRT than patients with no deficits in set-shifting abilities at baseline; the quality of life of the former group was higher than that of the latter at follow-up. Conclusions: CRT seems to be promising in enhancing the effectiveness of concurrent treatment.

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Cognitive retraining for organizational impairment in obsessive–compulsive disorder

Cited by 89 publications

References 25 publications

A Systematic Review of Central Coherence in Young People with Anorexia Nervosa

A Systematic Review of Central Coherence in Young People with Anorexia Nervosa

Strategic memory in adults with anorexia nervosa: Are there similarities to obsessive compulsive spectrum disorders?

The Effectiveness of Cognitive Remediation Therapy in Patients with a Severe or Enduring Eating Disorder: A Randomized Controlled Trial

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