Cognitive profiles of extremely preterm children: Full‐Scale IQ hides strengths and weaknesses

Kaul, Ylva Fredriksson; Johansson, Martin; Månsson, Johanna; Stjernqvist, Karin; Farooqi, Aijaz; Serenius, Fredrik; Thorell, Lisa B.

doi:10.1111/apa.15776

Cited by 14 publications

(31 citation statements)

References 31 publications

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“…The tolerance of healthy term neonates with PKU is usually between 30 and 50 mg/kg, declining later in life to 10–20 mg/kg. In contrast, ELBW neonates with PKU have a much higher phenylalanine tolerance, especially during early postnatal growth with rapid weight gain 5,6 . Our ELBW neonates with PKU showed very high tolerance to phenylalanine (80–110 mg/kg) during rapid weight gain between weeks three and 12 of life.…”

Section: Discussionmentioning

confidence: 57%

“…With a birth rate around 110,000 neonates per year in our country of 10.5 million inhabitants, and a detection rate of positive neonatal screening for PKU of one per 5500 neonates, the chance of an infant having an ELBW and PKU is 1.7 per million. This explains why clinicians have limited experience of caring for ELBW neonates with PKU 1,5,6 . Untreated PKU can cause severe intellectual disability, epilepsy, attention deficit disorders and behavioural problems that begin in early infancy 6,7 .…”

Section: Discussionmentioning

confidence: 99%

“…The average incidence of PKU in Europe is approximately one in 10,000 live births 4 . The combination of both ELBW and PKU is very rare and most perinatology centres and, or, specialised PKU centres only have limited experience of nutrition in such cases 1,5,6 …”

Section: Introductionmentioning

confidence: 99%

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Extremely low birthweight neonates with phenylketonuria require special dietary management

et al. 2021

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Aim Extremely low birthweight (ELBW) neonates require a high protein intake, but this can be challenging in the very rare cases when they also have phenylketonuria (PKU). This is due to a lack of suitable parenteral nutrition or enteral formula. Our aim was to analyse tolerance to phenylalanine in these infants. Material There are approximately 110 000 children born in the Czech Republic each year. A neonatal screening programme from 2005 to 2020 found that 320 neonates had PKU, including 30 premature neonates with a birth weight of less than 2500 g. Results This study focused on three neonates who were born with ELBWs of 720, 740 and 950 g, respectively. Phenylalanine levels normalised in ELBW neonates with PKU within 1 week of the introduction of low‐phenylalanine parenteral or enteral nutrition. The tolerance to phenylalanine was very high (70–110 mg/kg) in the first months of life, due to a rapid weight gain, but significantly decreased during infancy. Conclusion Extremely low birthweight neonates with PKU need special dietary management. Regular assessments of phenylalanine are necessary during the first weeks of life to allow prompt dietary adjustments that reflect rapid weight gain and transitory high tolerance to phenylalanine.

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Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%

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Extremely low birthweight neonates with phenylketonuria require special dietary management

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“…1 Poor motor skills are known to affect participation, and physical and mental well-being. 20 Visual motor integration is dependent on perception and motor skills, but also requires planning and organisation. Each of these skills may function adequately in isolation, but the integration requires a higher level of functioning.…”

Section: Discussionmentioning

confidence: 99%

Antenatal steroids and neurodevelopment in 12‐year‐old children born extremely preterm

et al. 2021

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“…Phase (4) identifies and delimits the research studies, and presents the narrative in the flowchart in Figure 1 (for presenting phases ( 5) and (6), see Section 2.2). Phase (7) resulted in an earlier initial report from this study [30], which was followed by a discussion with knowledge users (phase (8)). For this rapid review, we use the term "phase" (not steps, as the original research by Khangura et al [25] calls these) to distinguish from the major steps guiding the literature search (last column in Figure 1).…”

Section: Methodsmentioning

confidence: 99%

Current Challenges Supporting School-Aged Children with Vision Problems: A Rapid Review

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Many children have undetected vision problems or insufficient visual information processing that may be a factor in lower academic outcomes. The aim of this paper is to contribute to a better understanding of the importance of vision screening for school-aged children, and to investigate the possibilities of how eye-tracking (ET) technologies can support this. While there are indications that these technologies can support vision screening, a broad understanding of how to apply them and by whom, and if it is possible to utilize them at schools, is lacking. We review interdisciplinary research on performing vision investigations, and discuss current challenges for technology support. The focus is on exploring the possibilities of ET technologies to better support screening and handling of vision disorders, especially by non-vision experts. The data orginate from a literature survey of peer-reviewed journals and conference articles complemented by secondary sources, following a rapid review methodology. We highlight current trends in supportive technologies for vision screening, and identify the involved stakeholders and the research studies that discuss how to develop more supportive ET technologies for vision screening and training by non-experts.

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Cognitive profiles of extremely preterm children: Full‐Scale IQ hides strengths and weaknesses

Abstract: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Cited by 14 publications

References 31 publications

Extremely low birthweight neonates with phenylketonuria require special dietary management

Extremely low birthweight neonates with phenylketonuria require special dietary management

Antenatal steroids and neurodevelopment in 12‐year‐old children born extremely preterm

Current Challenges Supporting School-Aged Children with Vision Problems: A Rapid Review

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