Cognitive impairment in people with previous COVID-19 infection: A scoping review

Bertuccelli, Margherita; Ciringione, Luciana; Rubega, Maria; Bisiacchi, Patrizia; Masiero, Stefano; Felice, Alessandra Del

doi:10.1016/j.cortex.2022.06.002

Cited by 49 publications

(29 citation statements)

References 72 publications

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“…These results are consistent with existing studies showing cognitive deficits in people affected by COVID-19 [ 35 , 36 ]. By now, the presence of long-lasting cognitive symptoms is evident, but the question of underlying mechanisms remains open: it is not clear both the cause of the pathological process itself and which functions are most susceptible to impairments [ 37 ]. The results of our study related to the cognitive sphere may somehow indicate the dynamics of the recovery process on a neurobiological level; in particular, deficits in inhibition may be related to the fact that brain regions involved in inhibitory processes recover relatively slower.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Mild COVID-19 on Executive Functioning and Mental Health Outcomes in Young Adults

et al. 2022

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COVID-19 is associated with a range of long-lasting symptoms related to cognitive and psycho-emotional spheres. Even mild cases of the disease can lead to persistent cognitive deficits and deterioration of the psycho-emotional state. The purpose of our study was to examine the presence and frequency of psycho-emotional disorders and cognitive deficits in students who recovered from mild form of COVID-19. A total of 40 COVID-19 survivors and 25 healthy controls participated in our study. We assessed three core cognitive functions (inhibition, working memory, task-switching), reaction time and motor speed. We also assessed depression, anxiety and fatigue with self-report questionnaires. The COVID-19 group manifested increased depression and decreased inhibition in comparison with the controls. Our results show that even in young adults who have recovered from mild COVID-19, there are persisting cognitive and psycho-emotional deficits.

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Section: Discussionmentioning

confidence: 99%

The Impact of Mild COVID-19 on Executive Functioning and Mental Health Outcomes in Young Adults

et al. 2022

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“…Previous COVID-19 infection is associated with cognitive impairment, with well-described patterns of impairment in memory, attention and executive functions [52]. Similarly, COVID-19 has been associated with exacerbating or accelerating dementia [23].…”

Section: Covid-19 and Dementiamentioning

confidence: 99%

Does covid-19 impair endogenous neurogenesis?

Kumaria¹,

Noah²,

Kirkman³

2022

Journal of Clinical Neuroscience

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“…Neurological manifestations in people with COVID-19 (PwCOVID) were demonstrated from the beginning of the pandemic [ 2 ]; a percentage between 5% and 40% of PwCOVID presented some neurological manifestations, with central involvements being more common [ 3 ]. In particular, PwCOVID may present disorders of consciousness, acute cerebrovascular disease and, predominantly, cognitive impairment [ 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

The Coronavirus Footprint on Dual-Task Performance in Post-Acute Patients after Severe COVID-19: A Future Challenge for Rehabilitation

Giardini

Arcolin

Godi

et al. 2022

IJERPH

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Recent studies suggest that also the non-critical form of COVID-19 infection may be associated with executive function impairments. However, it is not clear if they result from cognitive impairments or by COVID-19 infection per se. We aimed to investigate if patients in the post-acute stage of severe COVID-19 (PwCOVID), without manifest cognitive deficits, reveal impairments in performing dual-task (DT) activities compared to healthy controls (HS). We assessed balance in 31 PwCOVID vs. 30 age-matched HS by stabilometry and the Timed Up and Go (TUG) test with/without a cognitive DT. The DT cost (DTC), TUG test time and sway oscillations were recorded; correct cognitive responses (CCR) were calculated to evaluate cognitive performance. Results show a significant difference in overall DT performance between PwCOVID and HS in both stabilometry (p < 0.01) and the TUG test (p < 0.0005), although with similar DTCs. The main difference in the DTs between groups emerged in the CCR (effect size > 0.8). Substantially, PwCOVID gave priority to the motor task, leaving out the cognitive one, while HS performed both tasks simultaneously. Our findings suggest that PwCOVID, even without a manifest cognitive impairment, may present a deficit in executive function during DTs. These results encourage the use of DTs and CCR in PwCOVID.

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Cognitive impairment in people with previous COVID-19 infection: A scoping review

Cited by 49 publications

References 72 publications

The Impact of Mild COVID-19 on Executive Functioning and Mental Health Outcomes in Young Adults

The Impact of Mild COVID-19 on Executive Functioning and Mental Health Outcomes in Young Adults

Does covid-19 impair endogenous neurogenesis?

The Coronavirus Footprint on Dual-Task Performance in Post-Acute Patients after Severe COVID-19: A Future Challenge for Rehabilitation

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