Cognitive functioning in obsessive-compulsive disorder: a meta-analysis

Abstract

Patients with OCD appear to have wide-ranging cognitive deficits, although their impairment is not so large in general. The different test forms and methods of testing may have influenced the performance of patients with OCD, indicating the need to select carefully the test forms and methods of testing used in future research. The effects of various confounding variables on cognitive functioning need to be investigated further and to be controlled before a definite conclusion can be made.

Further evidence of a dissociation between decision-making under ambiguity and decision-making under risk in obsessive–compulsive disorder

“…Further, the patients in their study were not impaired on the executive function tasks. Considering that there is substantial evidence of reduced executive function in OCD (Kashyap et al, 2013;Olley et al, 2007;Shin et al, 2014;Tukel et al, 2012), a caveat must be mentioned in generalizing the previous results. However, replication of intact GDT performance in a larger sample of OCD patients in the present study may verify the ability to make beneficial choices under explicit conditions in OCD.…”

Visuospatial Memory Improvement after Gamma Ventral Capsulotomy in Treatment Refractory Obsessive–Compulsive Disorder Patients

“…Therefore, in our sample, GVC not only showed efficacy in reducing OCS in treatment refractory OCD patients, but was also safe from a neuropsychological perspective. Several studies have identified VSM as a specific and central neuropsychological deficit in OCD (Bloch et al, 2011;Grisham et al, 2009;Kuelz et al, 2004Kuelz et al, , 2006Kim et al, 2002;Penadés et al, 2005;Purcell et al, 1998;Rao et al, 2008;Segalàs et al, 2008;Shin et al, 2013). Cross-sectional studies have shown that OCD patients present difficulties in VSM when compared with healthy controls (Kuelz et al, 2004;Purcell et al, 1998;Rao et al, 2008;Savage et al, 1999), and longitudinal studies indicate the presence of visuospatial deficits even before the onset of symptoms (Bloch et al, 2011;Grisham et al, 2009).…”

“…Kuelz et al (2008) found that major responders to treatment improved significantly more than minor responders on the ROCF immediate and delayed recall. Indeed, a recent meta-analysis on neuropsychological data and OCD has indicated that VSM is the most consistently cognitive improvement in OCD (ie, VSM presented the largest effect size among all neuropsychological domains; Shin et al, 2013).…”

Neuropsychological differences between obsessive-compulsive washers and checkers: A systematic review and meta-analysis

“…Two recent meta-analyses reported that OCD patients exhibited significant but moderate deficits in the domains of attention (Abramovitch, Abramowitz, & Mittelman, 2013), executive functions, verbal and nonverbal memory, visuospatial abilities, processing speed, and working memory compared to healthy controls (Abramovitch et al, 2013;Shin, Lee, Kim, & Kwon, 2014). In a critical review, Kuelz, Hohagen, and Voderholzer (2004) reported visuospatial memory deficits and using more complex tasks, also verbal memory deficits in OCD, both presumably due to underlying encoding deficits.…”