Cognitive function assessment in patients undergoing transcatheter aortic valve implantation

Proch, Marek; Olasińska-Wiśniewska, Anna; Łojko, Dorota; Grygier, Marek

doi:10.5114/nan.2016.65644

Cited by 1 publication

(3 citation statements)

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“…Younger age and longer education time are the common protective factors against dementia which strengthen everyday life activity skills, independence and autonomy. Our results are in line with those proving preserved neurocognitive domains longitudinally after TAVI [11][12][13][14]. Musa et al [11] in an observational two-center comparison found a decline in verbal memory and psychomotor speed at 30 days in a group of patients who received a second-generation Lotus valve.…”

Section: Discussionsupporting

confidence: 91%

“…However, performance longitudinally at 1 year was preserved in all neurocognitive domains with either prosthesis. Other studies presented [14,15] cognitive improvement after TAVI in patients with initially impaired preprocedural CF. Change in mental status was possibly related to hemodynamic improvement.…”

Section: Discussionmentioning

confidence: 95%

“…Better memory and attention functions possibly also improve everyday communication and cooperation between an elderly patient and a caregiver in usual activities, self-care and other activities of daily living. Preserved cognitive performance after TAVI suggests effectiveness of this treatment, even though the incidence of silent cerebral microinfarctions, lesions and hypoperfusion in the central nervous system as side effects are mentioned in some studies [11,14]. CF remained at the same level or improved in all TAVI patients in the 13-month follow-up.…”

Section: Discussionmentioning

confidence: 97%

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Changes in cognitive functions and quality of life in patients after transcatheter aortic valve implantation

Olszewska-Turek¹,

Tokarek²,

Dziewierz³

et al. 2020

pwki

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Introduction: Transcatheter aortic valve implantation (TAVI) has emerged as a therapeutic option for patients with severe aortic stenosis (AS). However, an association between cognitive functions (CF) and health-related quality of life (HRQoL) in TAVI patients is still unclear. Aim: To assess the long-term changes in CF and HRQoL in elderly patients with AS after TAVI. Material and methods: A total of 259 patients who underwent cardiological and psychological TAVI qualification were enrolled and divided into the normal (n = 174) and impaired cognition group (n = 85). CF and HRQoL characteristics assessed at baseline and 13 months were compared between groups. The analysis of multiple linear regression was performed to identify the association between HRQoL and CF and to assess the influence of TAVI on HRQoL. Results: There was no difference in CF between baseline and follow-up. However, an improvement in attention functions and memory skills in the cognitively impaired group was noted at follow-up. In addition, HRQoL scores increased in both groups. An independent predictor associated with HRQoL was global CF (β =-213, p = 0.01), which explained 7% of CF variation. Improvements in all five dimensions of HRQoL, from 4.8% in self-care and up to 33.6% in pain/discomfort, were found. At follow-up, 60% of TAVI patients had improved health, 12% had worse health, 4% showed no change and 24% had a "mixed" change. Conclusions: TAVI is associated with positive changes in the functioning of elderly patients at long-term follow-up.

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