Cognitive Examination In Thalassemia Patients

Abstract

Background: Many studies on thalassemia patients have shown cognitive decline that may affect the patients’ life. To clarify the cognitive value in thalassemia patients, we performed a neuropsychological test on these patients. Methods: This was a prospective observational analytic with case control study involving 40 thalassemia patients and 40 controls similar for age, sex, and education. All subjects underwent a comprehensive neuropsychological test including visual cognitive assessment. Results: Compared to controls, patients with thalassemia aged 15-47 years old had poorer results in world list recall (p=0.026), TMT-B (p=0.042), clock drawing test (p=0.049), ADAS-Cog (p=0.014), logical memory (p=0.001) and digit symbol (p<0.001). These results indicate that thalassemia patients have significantly lower attention, verbal memory capability, and executive function. Conclusion: Our findings concluded that patients with thalassemia have impaired multiple cognitive domains.

Design and Implementation of Distributed Resource Management and Platform Deployment Based on Logical Clock

“…The logical clock c can be expressed as a two-tuple, where Ic represents the set of moments, which is a total order on Ic, and the subscript can be omitted when there is no ambiguity. Based on logical time, CCSL only cares about the order relationship between moments, not the exact physical time interval between two moments [6][7]. Obviously, workers are discrete, according to <.…”