Cognitive-Emotional Training as an Intervention for Major Depressive Disorder

Iacoviello, Brian M.; Wu, Gang; Alvarez, Evan; Huryk, Kathryn M.; Collins, Katherine A.; Murrough, James W.; Iosifescu, Dan V.; Charney, Dennis S.

doi:10.1002/da.22266

Cited by 78 publications

(66 citation statements)

References 50 publications

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“…However, in contrast to previous studies, Iacoviello et al (2014) did not find significant effects of CCT on self-reported levels of rumination. Given the limited sample size (see Supplemental material Table 2), the lack of training effects on rumination might be due to limited power.…”

Section: Cognitive Control Training In Mdd Samplescontrasting

confidence: 99%

“…However, an important question that remains unaddressed is whether CCT interventions for depression should focus on increasing general cognitive control, or directly target cognitive control in the context of emotional information processing. In a recent double-blind RCT study, Iacoviello et al (2014) tested the superiority of an emotional CCT over a non-emotional CCT. At the end of four weeks of training, both training groups showed a similar increase in cognitive control, but only the emotional CCT group was characterized by a reduced memory bias for negative self-referent information.…”

Section: Cognitive Control Training In Mdd Samplesmentioning

confidence: 99%

“…Furthermore, with the exception of some studies that have shown to be adequately powered for the presented analyses, a substantial amount of CCT studies have relied on limited sample sizes, which has resulted in not being able to consistently detect moderate effects of CCT on rumination (e.g., d = 0.66; Iacoviello et al, 2014) and depressive symptomatology (e.g., d = 0.67; Trapp et al, 2016). These factors may have led to an underestimation of training effects in the latter studies.…”

Section: Critical Appraisal Of the Evidencementioning

confidence: 99%

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Cognitive control interventions for depression: A systematic review of findings from training studies

Koster

Hoorelbeke

Onraedt

et al. 2017

Clinical Psychology Review

209

159

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There is a strong interest in cognitive control training as a new intervention for depression.Given the recent promising meta-analytical findings regarding the effects of cognitive training on cognitive functioning and depressive symptomatology, the current review provides an indepth discussion of the role of cognitive control in depression. We consider the state-of-theart research on how manipulation of cognitive control may influence cognitive and depression-related outcomes. Evidence for the effectiveness of cognitive control training procedures are discussed in relation to three stages of depression (at-risk, clinically depressed, remission) as well as the training approach that was deployed, after which the putative theoretical mechanisms are discussed. Finally, we provide ways in which cognitive control training can be utilized in future research.COGNITIVE CONTROL TRAINING FOR DEPRESSION 3

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Section: Cognitive Control Training In Mdd Samplescontrasting

confidence: 99%

Section: Cognitive Control Training In Mdd Samplesmentioning

confidence: 99%

Section: Critical Appraisal Of the Evidencementioning

confidence: 99%

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Cognitive control interventions for depression: A systematic review of findings from training studies

Koster

Hoorelbeke

Onraedt

et al. 2017

Clinical Psychology Review

209

159

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“…In anxious adults, Amir and colleagues (in press) found that not only were features of covert and overt bias dynamics correlated, but that the real-time, dynamic expressions of overt and covert attentional processes were significantly coupled from trial-to-trial; again, conventional covert and overt bias scores were not associated. In related work, attention bias variability was examined with respect to PTSD (Iacoviello et al, 2014;Naim et al, 2015), providing further evidence for the utility of a dynamic process perspective on attention bias in psychopathology. Accordingly, in so far as this conceptual and computational approach better represents the nature of attentional dysregulation in the processing of threat theorized to be important in the maintenance of social anxiety disorder, this perspective may be key to help to elucidate the role(s) of attention bias in therapeutic change over the course of CBT for social Attention bias and CBT 8 anxiety.…”

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confidence: 99%

Attention bias dynamics and symptom severity during and following CBT for social anxiety disorder.

Davis¹,

Rosenfield²,

Bernstein³

et al. 2016

Journal of Consulting and Clinical Psychology

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Objective: Threat-related attention bias figures prominently in contemporary accounts of the maintenance of anxiety disorders, yet longitudinal intervention research relating attention bias to anxiety symptom severity is limited. Capitalizing on recent advances in the conceptualization and measurement of attention bias, we aimed to examine the relation between attention bias, indexed using trial-level bias scores (TLBSs) to quantify temporal dynamics reflecting dysregulation of attentional processing of threat (as opposed to aggregated mean bias scores) and social anxiety symptom severity over the course of cognitive–behavioral therapy (CBT) and 1-month follow-up. Method: Adults with social anxiety disorder (N = 39) assigned to either yohimbine- or placebo-augmented CBT completed measures of attention bias and social anxiety symptom severity weekly throughout CBT (5 sessions) and at 1-week and 1-month posttreatment. Results: TLBSs of attention bias temporal dynamics showed stronger psychometric properties than mean aggregated scores and were highly interrelated, in line with within-subject temporal variability fluctuating in time between attentional overengagement and strategic avoidance from threat. Attention bias toward threat and temporal variability in attention bias (i.e., attentional dysregulation), but not attention bias away from threat, significantly reduced over the course of CBT. Cross-lag analyses revealed no evidence of a causal relation between reductions in attentional dysregulation leading to symptom severity reduction, or vice versa. Observed relations did not vary as a function of time. Conclusions: We found no evidence for attentional dysregulation as a causal mechanism for symptom reduction in CBT for social anxiety disorders. Implications for future research are discussed.

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“…Recently, research has been conducted as to whether an increase in executive control would decrease depression symptoms. Prominent studies including those of Iacoviello et al [17], Hoorelbeke and Koster [15], and Siegle et al [18] have investigated benefits of cognitive control training as a therapy for depression.…”

Section: Research On Cognitive Control Therapymentioning

confidence: 99%

Cognitive Control Therapy as a Depression Treatment: a Review of the Literature

Davis¹

2017

Acta Psychopathol

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Recent investigations have explored the link between depression and executive function (the ability to process and organise information in order to achieve a goal). The specific aspect of executive function that is linked to depression is executive control, which includes the ability to regulate cognitive processes such as emotion. Research has found that subjects with greater levels of executive control are more likely to be able to control their reactions to stressful events and are less likely to develop depressive symptoms. As a result of these findings, cognitive control training has been suggested as a possible new treatment for depression. Further research in this field would be highly beneficial for the development of new and effective treatments for depression.

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Cognitive-Emotional Training as an Intervention for Major Depressive Disorder

Abstract: Cognitive-emotional training may represent a feasible and effective intervention strategy for MDD. This proof-of-concept study highlights the need for future studies to fully understand the effectiveness, and mechanisms of effect, of these training strategies.

Cited by 78 publications

References 50 publications

Cognitive control interventions for depression: A systematic review of findings from training studies

Cognitive control interventions for depression: A systematic review of findings from training studies

Attention bias dynamics and symptom severity during and following CBT for social anxiety disorder.

Cognitive Control Therapy as a Depression Treatment: a Review of the Literature

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