Cognitive Effects of Nutritional Deficiency

Rosenthal, Mark J.; Goodwin, James S.

doi:10.1007/978-1-4613-2529-1_3

Cited by 20 publications

(16 citation statements)

References 85 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been recognised for decades that micronutrient status can influence cognitive function across the lifespan, including that insufficient vitamin intake can impair several aspects of cognitive functions and mood [1,2,3,4,5,6,7,8]. In particular, the dietary status of certain B vitamins (e.g., folate, vitamins B6 and B12) has been positively associated with aspects of cognition, such as information processing, recall and verbal ability in healthy women of various ages [9].…”

Section: Introductionmentioning

confidence: 99%

Acute Effects of Different Multivitamin Mineral Preparations with and without Guaraná on Mood, Cognitive Performance and Functional Brain Activation

et al. 2013

View full text Add to dashboard Cite

Previous work has identified the positive effects of the acute administration of a multivitamin-guaraná preparation during an effortful executive/working memory task. Here, we aimed to differentiate the effects of multivitamins with and without guaraná and to examine the neural substrates of such effects using functional magnetic resonance imaging (fMRI). Following a double-blind, placebo-controlled, randomised, balanced crossover design, 20 participants (mean age 29 ± 5.54 years) consumed multivitamin preparations with or without guaraná (Berocca® Performance and Boost, respectively) and a placebo. Thirty minutes post-treatment, they underwent neurocognitive assessment, consisting of a 10 min Cognitive Demand Battery, with mood ratings taken immediately before and after the battery. Five additional participants underwent post-treatment fMRI scanning during Rapid Visual Information Processing and Inspection Time activation tasks. The multivitamin with guaraná treatment was associated with significantly enhanced Serial Threes performance and self-rated contentment. fMRI revealed that both multivitamin treatments increased activation in areas associated with working memory and attentional processing, with the effect being greater in the multivitamin with guaraná condition. These data confirm the acute benefits of multivitamins with guaraná on mood and cognitive performance. Furthermore, they demonstrate for the first time increased brain activation from multivitamin preparations both with and without guaraná, as measured using fMRI.

show abstract

Section: Introductionmentioning

confidence: 99%

Acute Effects of Different Multivitamin Mineral Preparations with and without Guaraná on Mood, Cognitive Performance and Functional Brain Activation

et al. 2013

View full text Add to dashboard Cite

show abstract

“…The profound interactions among nutrition, cognitive functions, and health have been recognized already many decades ago. Micronutrient status can affect cognitive function at all ages, and an insufficient vitamin supply can impair several aspects of cognitive functions and mood (Bellisle et al, 1998;Black, 2003;Heseker et al, 1995;Huskisson et al, 2007a;Malouf and Grimley Evans, 2008;Rosenberg and Miller, 1992;Rosenthal and Goodwin, 1985;Zimmermann et al, 2006). Vitamin and mineral deficiencies can lead to irreversible effects when occurring during pregnancy (Black, 2003), to impaired learning and cognitive functions when occurring during infancy/childhood (Black, 2003;Manger et al, 2004;Zimmermann et al, 2006), and to depression and dementia in the elderly (Rosenberg and Miller, 1992;Vollset and Ueland, 2005).…”

Section: Micronutrients For Mental and Physical Capacitymentioning

confidence: 96%

Ginseng and Micronutrients for Vitality and Cognition

Maggini

Spitzer

2013

Bioactive Food as Dietary Interventions for the Aging Population

View full text Add to dashboard Cite

“…Low folate status has been associated with megaloblastic anemia, small intestinal histological abnormalities, and changes in affective or cognitive status [8][9][10]. Because of the high reported prevalence of suboptimal folate status in some studies, and the potential target organ dysfunction, we offered screening with a single determination of serum folic acid.…”

Section: Introductionmentioning

confidence: 99%

Low serum folic acid levels in a nursing home population: a clinical experience.

Drinka

Langer

Voeks

et al. 1993

Journal of the American College of Nutrition

View full text Add to dashboard Cite

Four hundred fifty-five residents of the Wisconsin Veterans Home had fasting serum specimens obtained for folic acid as part of standard practice. Twenty-nine percent were taking folic acid supplements. Six percent (n = 28) were taking phenytoin, a folate antagonist. No resident receiving a folate supplement (400 mcg/day) had a low serum folic acid level. This finding may be important for practitioners selecting a dose of folic acid for nursing home patients. Of the 325 residents not receiving a folate supplement, nine (3%) had low folic acid levels (< 2.5 ng/mL). Two of the nine were receiving phenytoin. Five were characterized by staff as eating well. As low serum levels are preventable with a multivitamin, we believe that supplementation with a multivitamin containing 400 mcg folic acid/day should be considered in nursing home residents.

show abstract

Cognitive Effects of Nutritional Deficiency

Cited by 20 publications

References 85 publications

Acute Effects of Different Multivitamin Mineral Preparations with and without Guaraná on Mood, Cognitive Performance and Functional Brain Activation

Acute Effects of Different Multivitamin Mineral Preparations with and without Guaraná on Mood, Cognitive Performance and Functional Brain Activation

Ginseng and Micronutrients for Vitality and Cognition

Low serum folic acid levels in a nursing home population: a clinical experience.

Contact Info

Product

Resources

About