Cognitive-behavioural therapy for the management of inflammatory bowel disease-fatigue: a feasibility randomised controlled trial

Artom, Micol; Czuber‐Dochan, Wladyslawa; Sturt, Jackie; Proudfoot, Hannah; Roberts, D.; Norton, Christine

doi:10.1186/s40814-019-0538-y

Cited by 25 publications

(24 citation statements)

References 110 publications

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“…16 Meanwhile, in December 2019, the pilot trial on cognitive-behavioural therapy for the management of IBD-fatigue by Artom et al has also been published. 17 The same evaluation was done for pharmaceuticaldriven studies in the past 3 years. In total, 63 studies were found using the ClinicalTrials.…”

Section: Resultsmentioning

confidence: 99%

Are we addressing the top 10 research priorities in IBD?

Geldof

LeBlanc

Lucaciu

et al. 2020

Frontline Gastroenterol

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BackgroundSince publication of the top 10 research priorities in inflammatory bowel disease (IBD) based on the James Lind Alliance Priority Setting Partnership, the question remains whether this has influenced the IBD-research landscape. This study aimed to create an overview of the current distribution of research interests of trials in the UK.MethodsThe ClinicalTrials.gov database and European Union Clinical Trials Register were screened for clinical trials set up from 9 August 2016 to 16 November 2019 in the UK involving adult patients with IBD.ResultsOf 20 non-industry-sponsored studies, a quarter investigated treatment strategies considering efficacy, safety and cost-effectiveness (priority 1). Four evaluated the role of diet (priorities 3 and 7). Development/assessment of biomarkers for patient stratification (priority 2) and fatigue (priority 8) were subject of three studies. IBD-related pain and control of diarrhoea/incontinence were each subject of 2 studies (priorities 4 and 6). The effect of gut microbiota (priority 10) and optimal strategy for perianal Crohn’s disease (priority 5) was the focus of 2 studies each. One study evaluated surgery for terminal ileal Crohn’s disease (priority 9). Of 63 industry-sponsored studies, 59 focused on priority 1.ConclusionsThis study presents an impression of the breadth of the IBD-research landscape in the UK, in light of the top 10 research priorities published in 2016. Optimal treatment strategy has been the most studied research priority by academic and industry-sponsored trials. Fewer studies focused on patient-reported outcomes. It remains debatable to what extent the current research landscape adequately represents all stakeholders’ viewpoints on needs for expanded knowledge in IBD, particularly the patients’ perspective.

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Section: Resultsmentioning

confidence: 99%

Are we addressing the top 10 research priorities in IBD?

Geldof

LeBlanc

Lucaciu

et al. 2020

Frontline Gastroenterol

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“…Based on this knowledge and their willingness to reduce the burden on respondents, they decided to proceed and modify the time commitment requirement. 36 We found only a few examples of recruitment feasibility studies in health disparities or diverse populations. Thus, most of our examples are from studies of less diverse populations.…”

Section: Discussionmentioning

confidence: 99%

Guidelines for Evaluating the Feasibility of Recruitment in Pilot Studies of Diverse Populations: An Overlooked but Important Component

et al. 2020

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Background: In health disparities research, studies often fall short of their recruitment goals. Conducting a pilot feasibility study of recruitment in which data are collected systematically on recruitment processes can help investigators refine methods for the larger study. However, there are few guidelines for conducting pilot feasibility studies, and recruitment methods are seldom the focus. Feasibility indicators differ from traditional reports of recruitment results by focusing on the extent to which recruitment goals are met.Methods: We present an organizing framework for assessing the feasibility of recruitment that includes eight steps, briefly: 1) specify recruitment goals; 2) specify recruitment processes; 3) establish a tracking system for each individual; 4) establish a tracking database for monitoring processes and results; 5) implement recruitment and track each individual’s progress; 6) summarize recruitment results; 7) calculate and interpret feasibility measures - were goals met; and 8) if goals were not met, utilize tracking data to modify methods for the larger study. We describe methods within each step, with added details for steps 2-5 (the specific processes). The framework draws from a small literature on recruitment feasibility with a focus on health disparities populations. The guidelines blend well-known methods of recruitment with additional information on calculating feasibility indicators.Conclusion: These guidelines provide a first step in thinking systematically about recruitment feasibility, to advance the field of measuring feasibility. Feasibility indicators also can be used to track the effectiveness of innovative recruitment strategies as part of building the science of recruitment, especially in disparities populations. Ethn Dis. 2020; 30(Suppl 2):745-754; doi:10.18865/ed.30.S2.745

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“…Some researchers have focused on psychological factors, beliefs, and stress as causes and potential triggers [9,10]. Others have been curious about the e cacy of psychotherapeutic interventions for health amelioration, improved disease management, and even healing [11][12][13]. The outcomes of the research on the psychological issues prompted by this condition has not achieved unanimous agreement.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis and Psychotherapeutic Needs by Freiburg Personality Inventory in Inflammatory Bowel Disease

Rada

Gheonea

Popa

et al. 2021

Preprint

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Background Despite recent discoveries in pharmacotherapy and psychotherapy, patients with inflammatory bowel disease (IBD) still face challenges with improvement, remission, and healing. The objectives of the study were to identify the characteristics of patients with IBD with the Freiburg Personality Inventory and the intensity of the colonic disease, comorbidities, and other factors that could be related to the personality of the subjects.Methods Data were collected in the period 2019–2020 from 46 patients from records at two hospitals. This study used nonparametric methods, such as the Wilcoxon-Mann–Whitney, Kolmogorov–Smirnov, Mann–Whitney U test, and BOOTSTRAP method. The control group was considered the national normative sample based on the average raw scores on the 12 personality assessment scales using the t test (one sample t test).Results Compared to the control group, the Inhibitedness, Health Concerns, and Emotionality scales had significantly higher raw scores. Additionally, the Social Orientation, Frankness, and Extraversion scales had significantly lower raw scores. Health status was a medical factor that influenced personality scales. On the Somatic Complaints scale, patients who had lesions or comorbidities had significantly higher raw scores. Patients who had comorbidities in addition to IBD had considerably higher raw scores on the Excitability scale.Conclusions Positive affective and cognitive adjustment interventions may aid people with IBD in managing life problems in a balanced manner while interpreting treatment outcomes with confidence. Psychotherapeutic change interventions regarding life perception are required to tackle the description of subjective suffering related to physical inconveniences (Somatic Complaints scale), a strong orientation toward performance (Strain scale), mood swings, anxiety, and pessimism (Emotionality scale). Another intervention is reconsidering values and (re)prioritization, such as family, intimate relationships, friends, health, growth, development, balanced work, all of which can promote a feeling of well-being and balance.

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Cognitive-behavioural therapy for the management of inflammatory bowel disease-fatigue: a feasibility randomised controlled trial

Cited by 25 publications

References 110 publications

Are we addressing the top 10 research priorities in IBD?

Are we addressing the top 10 research priorities in IBD?

Guidelines for Evaluating the Feasibility of Recruitment in Pilot Studies of Diverse Populations: An Overlooked but Important Component

Diagnosis and Psychotherapeutic Needs by Freiburg Personality Inventory in Inflammatory Bowel Disease

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