BackgroundPersistent post-concussional symptoms (PCS) can be a source of distress and disability following traumatic brain (TBI). Such symptoms have been viewed as difficult to treat but may be amenable to psychological approaches such as cognitive behaviour therapy (CBT).
ObjectivesTo evaluate the effectiveness of a 12-session individualised, formulation-based CBT program.
MethodTwo-centre randomised waiting list controlled trial with 46 adults with persistent PCS after predominantly mild-to-moderate TBI (52% with PTA ≤ 24 hours), but including some with severe TBIs (20% with PTA > 7 days).
ResultsImprovements associated with CBT were found on the primary outcome measures relating to quality of life (using the Quality of Life Assessment Schedule and the Brain Injury Community Rehabilitation Outcome scale). Treatment effects after covarying for treatment duration were also found for postconcussional symptoms and several secondary outcomes including measures of anxiety and fatigue (but not depression or PTSD). Improvements were more apparent for those completing CBT sessions over a shorter period of time, but were unrelated to medicolegal status, injury severity or length of time since injury.
ConclusionsThis study suggests that CBT can improve quality of life for adults with persistent PCS, and potentially reduce symptoms for some, in the context of outpatient brain injury rehabilitation services.Trial registration ISRCTN49540320