Cognitive Assessment and Rehabilitation for Pediatric-Onset Multiple Sclerosis: A Scoping Review

Lin, Wei−Sheng; Lin, Shan-Ju; Hsu, Ting-Rong

doi:10.3390/children7100183

Cited by 5 publications

(1 citation statement)

References 50 publications

(111 reference statements)

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“…Yeh, et al [45] for instance, reported that parents of CAMS perceived the school related performance of their child to be poorer as compared to parents of age-matched healthy controls. Here, mismanagement of time because of fatigue-related symptoms, the negative impact of fatigue on mental health, and lack of knowledge regarding how to manage fatigue-related symptoms were reported by caregivers as some factors leading to poorer school-related performance in CAMS [18,39,57,58]. Moreover, to add towards the burden of MS, a lack of awareness among teachers was reported in some of the studies reviewed [18,29,33,39].…”

Section: Physical and Psychological Impact Of Msmentioning

confidence: 99%

Needs and Experiences of Children and Adolescents with Pediatric Multiple Sclerosis and Their Caregivers: A Systematic Review

et al. 2021

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In the present study we conduct a systematic review to evaluate the needs and experience of people with pediatric multiple sclerosis (MS) and their caregivers. The literature search was conducted across 10 academic databases, adhering to PRISMA-P guidelines. Quality appraisal was conducted using the mixed method appraisal test for individual studies, and GRADE-CERQual to establish overall confidence of findings. Results were analyzed using a process of narrative synthesis. We identified 26 studies which included 2253 children/adolescents with MS (CAMS) and 1608 caregivers. MS was reported to negatively impact experiences for CAMS in domains such as of school performance, social relationships, mental health, and overall physical functioning. Specifically, fatigue and social support were reported as the most important barriers and facilitators for CAMS, respectively. In terms of caregiver experience, negative impacts were reported on social functioning, mental health, and quality of life. Additionally, lack of awareness concerning MS was one of the biggest challenges reported. Caregivers expressed needs for psychological and social support. This study provides the first evidence regarding the needs and experiences of CAMS and their caregivers. Findings can be used to address policy gaps for supporting families affected by pediatric MS.

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Section: Physical and Psychological Impact Of Msmentioning

confidence: 99%

Needs and Experiences of Children and Adolescents with Pediatric Multiple Sclerosis and Their Caregivers: A Systematic Review

et al. 2021

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Effectiveness of Computerized Cognitive Rehabilitation Therapy on Cognitive Function of Children with Disabilities: A Systematic Review

Hong

Song

2023

Journal of Mental Health Research in Intellectual Disabilities

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Role of Ketogenic Diets in Multiple Sclerosis and Related Animal Models: An Updated Review

Lin

Liao

et al. 2022

Advances in Nutrition

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Prescribing a ketogenic diet (KD) is a century-old dietary intervention mainly used in the context of intractable epilepsy. The classic KD and its variants regained popularity in recent decades, and they are considered potentially beneficial in a variety of neurological conditions other than epilepsy. Many patients with multiple sclerosis have attempted diet modification for better control of their disease, whereas evidence thus far remains insufficient to recommend a specific diet for these patients. The results of three pilot clinical trials of KD therapy for multiple sclerosis, as well as several related studies, have been reported in recent years. The preliminary findings suggest that KD is safe, feasible, and potentially neuroprotective and disease-modifying for patients with multiple sclerosis. Research on corresponding rodent models also lent support to the efficacy of KD in the prevention and treatment of experimental autoimmune encephalomyelitis and toxin-induced inflammatory demyelinating condition in the brain. Furthermore, the animal studies yielded mechanistic insights into the molecular mechanisms of KD action in relevant situations, paving the way for precision nutrition. Herein we review and synthesize recent advances and also identify unresolved issues, such as the roles of adipokines and gut microbiota, in this field. Hopefully this panoramic view of current understanding could inform future research directions and clinical practice with regard to KD in MS and related conditions.

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Cognitive Assessment and Rehabilitation for Pediatric-Onset Multiple Sclerosis: A Scoping Review

Cited by 5 publications

References 50 publications

Needs and Experiences of Children and Adolescents with Pediatric Multiple Sclerosis and Their Caregivers: A Systematic Review

Needs and Experiences of Children and Adolescents with Pediatric Multiple Sclerosis and Their Caregivers: A Systematic Review

Effectiveness of Computerized Cognitive Rehabilitation Therapy on Cognitive Function of Children with Disabilities: A Systematic Review

Role of Ketogenic Diets in Multiple Sclerosis and Related Animal Models: An Updated Review

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