Cognitive Approaches to the Memory Disorders of Demented Patients

Heindel, William C.; Salmon, David P.

doi:10.1007/0-306-47377-1_30

Cited by 26 publications

(20 citation statements)

References 225 publications

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“…The disproportionate AD-related deficit in generating specific exemplars from a predefined category (e.g. a grocery store) as compared to generating words beginning with a certain letter has been interpreted to reflect the fact that category fluency places greater demands on the organization of the semantic network compared with letter fluency [57]. Specifically, whereas the search set that can be used to guide production in letter fluency is quite extensive, a much smaller set of exemplars within an abstract semantic category is available in the case of category fluency [58].…”

Section: Discussionmentioning

confidence: 99%

Negligible Effects of Depression on Verbal and Spatial Performance in Alzheimer’s Disease

Berger

Fahlander

Wåhlin

et al. 2001

Dement Geriatr Cogn Disord

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We examined whether a diagnosis of depression affects verbal and visuospatial performance in Alzheimer’s disease (AD). Using data from a population-based study, persons with AD and depression (AD/D), AD alone and a control group of normal older adults were compared in two tests of verbal ability (category and letter fluency) and two tests of visuospatial skill (block design and clock drawing). As expected, there were clear AD-related deficits across all cognitive tasks. More importantly, the AD and AD/D groups were indistinguishable on all task variables. The lack of effects of depression was discussed relative to the view that those symptoms of this disease which are especially detrimental to cognitive functioning (e.g. concentration difficulties, lack of interest, loss of energy) may already be present in AD as a result of the neurodegenerative process.

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Section: Discussionmentioning

confidence: 99%

Negligible Effects of Depression on Verbal and Spatial Performance in Alzheimer’s Disease

Berger

Fahlander

Wåhlin

et al. 2001

Dement Geriatr Cogn Disord

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“…Although Alzheimer's disease (AD) and Huntington's disease (HD) are both neurodegenerative disorders that cause global dementia syndromes, there is considerable evidence that distinct neurobehavioral and neurocognitive deficits are associated with the two diseases (Cummings, 1990;Cummings & Benson, 1983;Heindel & Salmon, 2001). AD is characterized by a prominent amnesia with secondary deficits in language, abstract reasoning, and visuospatial functioning (for review, see Salmon & Bondi, 1999).…”

Section: Introductionmentioning

confidence: 99%

Differential effects of Alzheimer's disease and Huntington's disease on the performance of mental rotation

Lineweaver

Salmon

Bondi

et al. 2005

J Int Neuropsychol Soc

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The ability to spatially rotate a mental image was compared in patients with Alzheimer's disease (AD; n = 18) and patients with Huntington's disease (HD; n = 18). Compared to their respective age-matched normal control (NC) group, the speed, but not the accuracy, of mental rotation abnormally decreased with increasing angle of orientation for patients with HD. In contrast, the accuracy, but not the speed, of rotation abnormally decreased with increasing angle of orientation for patients with AD. Additional analyses showed that these unique patterns of performance were not attributable to different speed/accuracy trade-off sensitivities. This double dissociation suggests that the distinct brain regions affected in the two diseases differentially contribute to speed and accuracy of mental rotation. Specifically, the slowing exhibited by HD patients may be mediated by damage to the basal ganglia, whereas the spatial manipulation deficit of AD patients may reflect pathology in parietal and temporal lobe association cortices important for visuospatial processing. (JINS, 2005, 11, 30-39.) 2

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“…puter mouse for all digits (1)(2)(3)(4)(5)(6)(7)(8)(9), with the exception of the number '3' . The no-go target (number '3') was presented a total of 25 times with a regularly paced 1,150-ms period from digit onset to the next digit onset.…”

Section: Sustained Attention To Response Taskmentioning

confidence: 99%

“…Memory impairment is one of the earliest presenting features seen in patients with Alzheimer's disease [1], with all aspects becoming progressively impaired. Remote memories of personally experienced events, unique to the individual, are often called autobiographical memories (ABMs).…”

Section: Introductionmentioning

confidence: 99%

“…If the predominant underlying mechanism related to anxiety, the state anxiety levels were expected to be reduced in the music condition, in line with previous research demonstrating the calming nature of music interventions. If arousal is the mediating factor underlying auditory enhancement of memory recall, tonic arousal levels 1 were predicted to be increased in the 1 Tonic arousal refers to relatively slow changes of base-level arousal, whereas phasic arousal is stimulus related, focused arousal, and more short- music stimulation condition, thus facilitating performance on the SART, whereby participants would exhibit less of the customary attentional lapses commonly noted on this task. It was expected that clear differences would be observed on one or more of these subtasks in order to extrapolate regarding the mediating mechanism that underlies the enhancing effect of auditory stimulation on cognition.…”

Section: Introductionmentioning

confidence: 99%

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Investigating the Enhancing Effect of Music on Autobiographical Memory in Mild Alzheimer’s Disease

Irish

Cunningham

Walsh

et al. 2006

Dement Geriatr Cogn Disord

216

166

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The enhancing effect of music on autobiographical memory recall in mild Alzheimer’s disease individuals (n = 10; Mini-Mental State Examination score >17/30) and healthy elderly matched individuals (n = 10; Mini-Mental State Examination score 25–30) was investigated. Using a repeated-measures design, each participant was seen on two occasions: once in music condition (Vivaldi’s ‘Spring’ movement from ‘The Four Seasons’) and once in silence condition, with order counterbalanced. Considerable improvement was found for Alzheimer individuals’ recall on the Autobiographical Memory Interview in the music condition, with an interaction for condition by group (p < 0.005). There were no differences in terms of overall arousal using galvanic skin response recordings or attentional errors during the Sustained Attention to Response Task. A significant reduction in state anxiety was found on the State Trait Anxiety Inventory in the music condition (p < 0.001), suggesting anxiety reduction as a potential mechanism underlying the enhancing effect of music on autobiographical memory recall.

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Cognitive Approaches to the Memory Disorders of Demented Patients

Cited by 26 publications

References 225 publications

Negligible Effects of Depression on Verbal and Spatial Performance in Alzheimer’s Disease

Negligible Effects of Depression on Verbal and Spatial Performance in Alzheimer’s Disease

Differential effects of Alzheimer's disease and Huntington's disease on the performance of mental rotation

Investigating the Enhancing Effect of Music on Autobiographical Memory in Mild Alzheimer’s Disease

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