Coffee or tea: Anti-inflammatory properties in the context of atherosclerotic cardiovascular disease prevention

Colonic Coffee Phenols Metabolites, Dihydrocaffeic, Dihydroferulic, and Hydroxyhippuric Acids Protect Hepatic Cells from TNF-α-Induced Inflammation and Oxidative Stress

“…Coffee has shown anti-hyperlipidemic, anti-hyperglicemic, and anti-hypertensive properties [ 19 , 20 ], although the effects on inflammation are inconsistent. According to a recent review [ 21 ], coffee consumption may have anti-inflammatory effects, and the discrepancy might be due to large heterogeneity of the available studies, with negative results mostly from short-term, very small trials, with small to moderate consumption of coffee. Based on large studies, it seems that coffee might exert some direct properties related to the reduction of inflammatory biomarkers, as confirmed in most systematic reviews and meta-analyses.…”

Trends and hotspots in tea and Alzheimer's disease research from 2014 to 2023: A bibliometric and visual analysis

“…Rich in caffeine and tea polyphenols [ 14 ], the advantageous attributes of tea are primarily ascribed to its robust polyphenol content, particularly catechin, renowned for its potent antioxidant capabilities [ 14 ]. Regardless of its variety, tea and its derivatives exhibit a spectrum of effects, including antibacterial qualities [ 15 ], anti-inflammatory attributes [ 16 ], antitumor potential [ 17 ], antiviral properties [ 18 ], and more. The documented ability of catechin's polyphenols to impede amyloid-beta aggregation and exhibit anti-apoptotic effects suggests a potentially substantial protective role against AD [ 13 , 14 ].…”

Main Colonic Metabolites from Coffee Chlorogenic Acid May Counteract Tumor Necrosis Factor-α-Induced Inflammation and Oxidative Stress in 3T3-L1 Cells

“…Apropos of the referred joint responses between oxidative stress and inflammation, the search for dietary compounds with antioxidant and anti-inflammatory activities as a natural alternative for the prevention of inflammation-related diseases has received significant attention during the past decade [ 15 ]. Coffee is a major source of phenolic compounds in Western countries [ 16 ], and its moderate consumption may have anti-inflammatory effects [ 17 ]. Cell culture studies suggest that the modest but significant anti-inflammatory effects of coffee could be mediated by hydroxycinnamic (chlorogenic) acids, the major phenolic component that has been proven to suppress the expressions of interleukins and cell adhesion molecules (vascular (VCAM-1) and intercellular (ICAM-1) cell adhesion molecules and E-selectin) induced by IL-1β [ 18 ] or lipopolysaccharide (LPS) [ 19 ].…”