Coffee consumption and the risk of lung cancer: an updated meta-analysis of epidemiological studies

Abstract

The present study suggested that coffee intake was associated with an increased risk of lung cancer.

Critical Dietary Factors in Cancer Chemoprevention

“…Early isoflavone exposure can protect against breast cancer as they may exert their putative protective effects by stimulating breast cell differentiation so isoflavone intake since childhood or adolescence may influence the risk of breast cancer incidence in adulthood (Messina and Wu 2009). As mentioned above, early life exposure to isoflavone in Asian women has protective effect on breast cancer risk Xie et al 2013) and has been associated with lower Her2/neu and proliferating cell nuclear antigen expression in malignant compared to benign breast tissue (Maskarinec et al 2009). Relatively small doses of soy throughout the day can keep an optimum steady-state serum isoflavone level, as opposed to a single dose at once.…”

“…Decrease in disease incidence was noted likely as a result of their ability to mimic natural estrogens, which are known to play a role in breast cancer progression (Pavese et al 2010). The Westerners' results may largely be attributed to the different amount of soy consumption which is obviously far below even the lower levels of intake in an Asian population (Xie et al 2013;. However, Dong and Qin (2011) described only 11 % decrease in risk of breast cancer incidence.…”

“…Many epidemiological studies explored this association but inconclusive results were obtained. Stronger inverse association of isoflavone consumption with breast cancer incidence in postmenopausal women than in premenopausal women was presented in more studies (Xie et al 2013;Nagata 2010;Yamamoto et al 2003). Isoflavone consumption did not affect estradiol or estrone, but it reduced FSH and LH in premenopausal women (Hooper et al 2009).…”

What is the relationship between coffee and lung cancer?

“…Dear Editor, I read the recent meta-analysis by Xie et al 1 in the February 2016 edition of the European Journal of Clinical Nutrition entitled, 'Coffee consumption and the risk of lung cancer: an updated meta-analysis of epidemiological studies.' This timely subject connecting the consumption of a widely consumed product and a dangerous disease is of great public health interest, and I commend Xie et al 1 for covering this subject as something so prevalent on a world-wide scale.…”

“…This timely subject connecting the consumption of a widely consumed product and a dangerous disease is of great public health interest, and I commend Xie et al 1 for covering this subject as something so prevalent on a world-wide scale. A meta-analysis of this topic helps to summarize the numerous and inconsistent findings of currently available research, highlighting areas requiring even further inquiry.…”