Coffee consumption and risk of the metabolic syndrome: A meta-analysis

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

“…The following factors have been reported as being inversely associated with incident metabolic syndrome, defined by 1 of the major definitions, in prospective or retrospective cohort studies: muscular strength, 179 increased PA or physical fitness, 134,180 aerobic training, 181 moderate alcohol intake, 86,100 fiber intake, 182 fruits and vegetables, 183 white fish intake, 184 Mediterranean diet, 185 dairy consumption 140 (particularly yogurt and low-fat dairy products 186 ), consumption of fermented milk with Lactobacillus plantarum , 187 animal or fat protein, 188 hot tea consumption (but not sugar-sweetened iced tea), 189 coffee consumption, 190 vitamin D intake, 191,192 intake of tree nuts, 193 avocado intake, 194 long-chain omega-3 polyunsaturated fatty acid, 195 potassium intake, 196 ability to interpret nutrition labels, 131 insulin sensitivity, 157 ratio of aspartate aminotransferase to ala-nine transaminase, 163 total testosterone, 153,157,197 serum 25-hydroxyvitamin D, 198 sex hormone–binding globulin, 153,157,197 and Δ5-desaturase activity. 199 In cross-sectional studies, increased standing, 200 a vegetarian diet, 201 subclinical hypothyroidism in males, 202 and marijuana use 203 were inversely associated with metabolic syndrome.…”

Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes

“…In general population, coffee consumption has been associated with beneficial health effects, including reduced risk of MS [4,5] and type 2 diabetes [8]. As MS is frequently observed also in T1D [2], and since it is an independent risk factor for cardiovascular complications [3], we wanted to elucidate whether there is an association between coffee consumption and MS also in this high- The reason behind the disparity between the observations made in general population and in the current study is not known.…”

“…Subjects were participants of the Finnish Diabetic Nephropathy (FinnDiane) Study, which aims to identify risk factors for long-term complications of T1D. Included in these cross-sectional analyses M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT 4 were all individuals with known MS status and a completed diet questionnaire (n=1040, age 46.7 ± 0.4 years, 45% men). Individuals with end-stage renal disease (dialysis or renal transplant) or eGFR <30 mmol/l were excluded.…”

“…In two meta-analyses, coffee consumption has been inversely related to the MS [4,5]. Particularly, a negative association between coffee consumption and the MS has been most evident in high habitual intakes, those exceeding 3 cups of coffee per day [6].…”

Treatment of NAFLD with diet, physical activity and exercise

“…74 Furthermore, it was demonstrated that chlorogenic acid, a main coffee polyphenol, inhibits hepatic stellate cells activation in vitro. 76 In epidemiological studies, coffee consumption is associated with a lower risk of metabolic syndrome, 77 and caffeinated and decaffeinated coffee is associated with reduced diabetes risk in a doseresponse manner. 78 Epidemiological studies in NAFLD patients indicate an inverse association between coffee consumption and liver fibrosis.…”