Coexisting rheumatoid arthritis and ankylosing spondylitis discussion of 3 cases with review of the literature

Toussirot, Éric; Acquaviva, P

doi:10.1007/bf02208154

Cited by 24 publications

(30 citation statements)

References 15 publications

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“…Anti-CCP were also present in other rheumatic conditions, being found in 10.6% of patients with psoriatic arthritis and 20.9% of patients with unclassified rheumatism in another study. 21 There are also case reports of concomitant diagnoses of seropositive RA and bilateral SII in some patients, 22,23 and the authors suggested that the prevalence of SpA features in patients with RA may be much higher than previously recognized.…”

Section: Discussionmentioning

confidence: 99%

Strongly positive anti‐CCP antibodies in patients with sacroiliitis or reactive arthritis post‐E. coli infection: A mini case‐series based review

2017

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We report here on four cases of patients with strongly positive anti-citrullinated cyclic peptides (anti-CCP) antibodies and clinical features of seronegative spondyloarthritis (SpA) and reactive arthritis. The four patients had various clinical presentations: one had an initial diagnosis of seropositive rheumatoid arthritis (RA) with involvement of the sacroiliac joints (similar to previous reports of the association of two diseases); one had a clinical picture of reactive arthritis following an episode of an Escherichia coli positive urinary tract infection; and two had asymmetrical sacroiliitis (SII), but no evidence of peripheral joint involvement (never reported before). In all cases, high titers of anti-CCP antibodies were found. We present a comparison of the clinical manifestations, radiographic features and treatment regimens of these cases. Our report supports previous literature data of possible overlap existing between RA and SpA, but also presents for the first time the association of high titers of anti-CCP antibodies with SII and reactive arthritis in patients with no peripheral small joint involvement.

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Section: Discussionmentioning

confidence: 99%

Strongly positive anti‐CCP antibodies in patients with sacroiliitis or reactive arthritis post‐E. coli infection: A mini case‐series based review

2017

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“…The influence of HLA-B27 antigen on the course of RA and the influence of HLA-DR4 on the course of AS is not clear. However, previous studies suggested that there is no erosive polyarthritis in RF positive AS patients, and sacroiliac joint involvement is not commonly seen in the positive HLA-B27 RA patients [4]. Some authors have suggested that AS and RA have identical or similarly causes, because of the various genetic backgrounds that lead a patient to develop AS or RA.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Association Ankylosing Spondylitis and Rheumatoid Arthritis: Case Report with Literature Review

Baccouche¹,

Bouzaoueche²,

Belghali³

2016

Rheumatology (Sunnyvale)

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The probability of one patient has ankylosing spondylitis (AS) and rheumatoid arthritis (RA) is low. It is usually difficult to diagnose the association, indeed we require a careful diagnostic process and more tests are needed. A 21-year-old female patient with coexisting AS and RA was reported here. 9 months later, she developed peripheral polyarthritis, erosion changes on the radiography of Metatarso-phalangeal (MTP), rheumatoid factor and cyclic citrullinated peptide antibody (anti-CCP) were positives. Here, we describe the diagnostic process that we followed.

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“…In contrast, AS was not associated with RA or SLE [21]. Information about the association of SpAs and RA is scarce, and few case reports have been published [22–24]. In 1981, one study including 184 patients with AS or RS showed that five of them had concomitant diagnostic of RA and two of these five patients presented also with Felty's syndrome [25].…”

Section: Discussionmentioning

confidence: 99%

Spondyloarthropathies in Autoimmune Diseases and Vice Versa

Perez-Fernandez

Mantilla

Cruz‐Tapias

et al. 2012

Autoimmune Diseases

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Polyautoimmunity is one of the major clinical characteristics of autoimmune diseases (ADs). The aim of this study was to investigate the prevalence of ADs in spondyloarthropathies (SpAs) and vice versa. This was a two-phase cross-sectional study. First, we examined the presence of ADs in a cohort of patients with SpAs (N = 148). Second, we searched for the presence of SpAs in a well-defined group of patients with ADs (N = 1077) including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren's syndrome (SS). Among patients with SpAs, ankylosing spondylitis was observed in the majority of them (55.6%). There were two patients presenting with SS in the SpA group (1.4%) and 5 patients with autoimmune thyroiditis (3.5%). The global prevalence of ADs in SpAs was 4.86%. In the ADs group, there were 5 patients with SpAs (0.46%). Our results suggest a lack of association between SpAs and ADs. Accordingly, SpAs might correspond more to autoinflammatory diseases rather than to ADs.

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Coexisting rheumatoid arthritis and ankylosing spondylitis discussion of 3 cases with review of the literature

Cited by 24 publications

References 15 publications

Strongly positive anti‐CCP antibodies in patients with sacroiliitis or reactive arthritis post‐E. coli infection: A mini case‐series based review

Strongly positive anti‐CCP antibodies in patients with sacroiliitis or reactive arthritis post‐E. coli infection: A mini case‐series based review

Diagnosis of Association Ankylosing Spondylitis and Rheumatoid Arthritis: Case Report with Literature Review

Spondyloarthropathies in Autoimmune Diseases and Vice Versa

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