Coexisting micronutrient deficiencies among Sri Lankan pre‐school children: a community‐based study

Hettiarachchi, Manjula; Liyanage, Chandrani

doi:10.1111/j.1740-8709.2010.00290.x

Cited by 33 publications

(45 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prevalence of other micronutrient deficiencies (e.g. Folate) have been described among Sri Lankan children which may be a cause for anemia in this sample also [26, 45]. However, higher prevalence of iron deficiency was predicted by peripheral blood film analysis of the current sample.…”

Section: Discussionmentioning

confidence: 62%

“…However, higher prevalence of iron deficiency was predicted by peripheral blood film analysis of the current sample. Higher prevalence of depleted iron stores in preschoolers and adolescents have been identified in other parts of the country [26, 45, 46]. Serum Ferritin depends on other factors such as presence of haemoglobinopathies [47] and inflammation [48].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Factors associated with anemia among Sri Lankan primary school children in rural North Central Province

et al. 2017

View full text Add to dashboard Cite

BackgroundDespite interventions, childhood anemia is still a major public health problem in low and middle income countries. Purpose of the present study is to determine factors associated with anemia among rural primary school children in Sri Lanka, a country undergoing rapid socioeconomic changes.MethodsMulti stage cluster sampling was used to select 100 rural schools in NCP and a maximum of 50 children aged 60–131 months were enrolled from each school. Self-administered questionnaires were sent to parents. Anthropometric measurements and blood samples were obtained by trained investigators. Blood reports were analyzed in a commercial laboratory with external quality control measures.ResultsTotal of 4412 children were included in the analysis. A Multiple regression was performed for hemoglobin. Only 4.2% of the change in hemoglobin could be explained by the model. District (p > 0.001), age (p > 0.001), timing of warm treatment(p = 0.026) and BMI for age (p = 0.002) uniquely contributed 1.12%, 1.19%, 0.13% and 0.26% to change in hemoglobin level respectively whereas, sex, monthly family income and frequency of meat and green leaf consumption didn’t contribute significantly.Peripheral blood film analyses were available for 146 anemic children. Blood film was reported as normal in 19.9% while evidence of iron deficiency (18.5%), early iron deficiency (32.5%) and thalassemia trait with iron deficiency (29.5%) were reported in the rest.Serum ferritin level was available for 417 children with hemoglobin less than 12 g/dl. Mean ferritin level was 63.7 microgram/l. Only 0.5% had depleted iron stores. A multiple regression was performed for serum ferritin and R2 was 0.123 (p < 0.001). Area under the curve for serum ferritin and anemia was 0.436.ConclusionAnemia among rural primary school children in NCP cannot be well explained by routinely assessed socioeconomic characteristics which mainly provide clues to access for food. Commonly used anemia related investigations have low validity in detecting and explaining anemia in this population. Since behavioral factors have been shown to affect nutrition of younger children in Sri Lanka, studying weather behaviors are related to anemia in primary school children is important. Possible etiologies including but not limited to nutritional deficiencies need to be studied further.

show abstract

Section: Discussionmentioning

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Factors associated with anemia among Sri Lankan primary school children in rural North Central Province

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Malnutrition is associated with micronutrient deficiencies [14,15]. Research has shown that supplementation to correct common micronutrient deficiencies such as iron, Vitamin A, Zinc or iodine deficiency is beneficial to children [16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Serum Selenium Levels and Nutritional Status of School Children from an HIV Prevention Programme in Zimbabwe

Kuona¹

2014

J Trop Dis

View full text Add to dashboard Cite

Nutrition programmes in resource poor settings mainly focus on children under the age of five years and this has resulted in limited information on nutritional and micronutrient status of school children in areas with high burden of HIV infection. This cross-sectional study assessed the prevalence of, and factors associated with stunting, thinness, overweight, underweight and selenium deficiency in school aged children from a high HIV burden peri-urban area in Zimbabwe, a low income country. Seven to 10 year old children from a prevention of mother-to-child transmission of HIV cohort had their serum selenium levels determined by mass spectrometry in a cross-sectional study. Height, weight, mid-upper-arm and head circumferences were measured to determine the prevalence of stunting, thinness, underweight and wasting. WHO growth standards were used to define the children's nutritional status. A total of 318 children including 21 (7%) HIV infected were assessed. The prevalence of stunting, thinness and underweight was 12%, 4% and 8% respectively. The prevalence of Selenium deficiency (serum Selenium <0.89 µmol/L) was 48% and it was found to be high in all the children despite their HIV status. Stunting was associated with HIV infection and orphan hood. There was no difference in height or weight between the HIV uninfected (exposed and unexposed) children who were in comparison both taller and heavier than the HIV infected children. Chronic malnutrition and selenium deficiency were prevalent in this cohort of children. Further studies are recommended to guide the need for selenium supplementation. Setting up health programmes to identify malnutrition in school aged children should be a priority.

show abstract

“…There are only few studies available on vitamin D status of Sri Lankan children. VDD using a higher cut off value (< 35 nmol/l) was seen in 26% and 25% of male and female children respectively in the Southern province of Sri Lanka [11]. A Similar study done more recently revealed VDD (< 20 nmol/l) in 29% of study population [12].…”

Section: Potential Explanations For the Association Between Low 25(ohmentioning

confidence: 59%

Vitamin D Supplementation in Obese Sri Lankan Children: A Randomized Controlled Trial

Samaranayake

Adikaram

Kendaragama

et al. 2020

Preprint

View full text Add to dashboard Cite

Background Micronutrient deficiencies are identified among obese individuals. Vitamin D deficiency is prevalent in obese children, and is hypothesized to cause insulin resistance and metabolic abnormalities. This study aimed to determine the effect of vitamin D supplementation on obesity and related metabolic abnormalities among obese Sri Lankan children.Methods A triple-blind randomized controlled trial was conducted among vitamin D deficient (< 20 ng/ml), obese children (n = 96). Children were randomly allocated to three intervention arms - treatment arm receiving weekly vitamin D2 50,000 IU; supplementation arm receiving 2500 IU weekly and control arm receiving placebo. Anthropometry, percentage fat mass (%FM) and blood pressure were assessed and fasting blood glucose, fasting insulin, lipid profile, ALT, AST, vitamin D, parathyroid hormone and hs-CRP and OGTT with 2-hour random blood glucose and insulin was performed at baseline and after 24 weeks of treatment. Ethics Review Committee of Faculty of Medicine, University of Colombo approved the protocol.Results Waist circumference Z-score, %FM and serum calcium significantly improved across all three arms, ALT significantly improved in treatment and supplementation arms while, BMI Z-score, PTH and vitamin D significantly improved in the treatment arm. Biceps (p = 0.035) and subscapular (0.048) skin fold thickness, vitamin D (p = 0.004) and ALT (p = 0.012) significantly improved in the treatment arm.Conclusions A strict dietary and physical activity regimen could improve some of the anthropometric, body composition and metabolic profiles, but high dose vitamin D, enhances those improvements. Therefore high dose vitamin D seems to potentiate management outcomes of obese children with vitamin D deficiency.Trial registration The study was registered at the Sri Lanka Clinical Trials Registry (SLCTR/2015/017) on 12th September 2015 at https://slctr.lk/trials/slctr-2015-017.

show abstract

Coexisting micronutrient deficiencies among Sri Lankan pre‐school children: a community‐based study

Cited by 33 publications

References 26 publications

Factors associated with anemia among Sri Lankan primary school children in rural North Central Province

Factors associated with anemia among Sri Lankan primary school children in rural North Central Province

Serum Selenium Levels and Nutritional Status of School Children from an HIV Prevention Programme in Zimbabwe

Vitamin D Supplementation in Obese Sri Lankan Children: A Randomized Controlled Trial

Contact Info

Product

Resources

About