2002
DOI: 10.1067/mjd.2002.108495
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Coexistence of pseudoxanthoma elasticum?like papillary dermal elastolysis and linear focal dermal elastosis

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Cited by 31 publications
(20 citation statements)
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“…1 Histology is characterized by a lack of oxytalan and eulanin elastic fibers in the papillary dermis. 2,3 Affected sites in PXE-PDE include chiefly flexural areas: the neck; supraclavicular region; scalp; axillae; lower aspect of abdomen/inguinal region; and antecubital fossa. 1,2,[4][5][6][7][8] Mild pruritus can occur in the involved region.…”
Section: Discussionmentioning
confidence: 99%
“…1 Histology is characterized by a lack of oxytalan and eulanin elastic fibers in the papillary dermis. 2,3 Affected sites in PXE-PDE include chiefly flexural areas: the neck; supraclavicular region; scalp; axillae; lower aspect of abdomen/inguinal region; and antecubital fossa. 1,2,[4][5][6][7][8] Mild pruritus can occur in the involved region.…”
Section: Discussionmentioning
confidence: 99%
“…Immunohistochemical staining may show loss of fibrillin-1 and -2 and microfibril-associated glycoprotein-1 and -2 in the papillary dermis. 99,101 These elastogenic changes may reflect an active repair process of elastolytic damage and are thought to be consistent with intrinsic or chronologic aging. 102 Associated conditions.…”
Section: Pseudoxanthoma Elasticumÿlike Papillary Dermal Elastolysismentioning
confidence: 97%
“…28,29 Elastin, fibrillin-1, fibrillin-2, and microfibril-associated glycoprotein-1 and -4 may be decreased in or absent from the papillary dermis of lesional skin. 30 Associated conditions. Linear focal elastosis has not been associated with systemic involvement.…”
Section: Linear Focal Elastosismentioning
confidence: 99%