Coexistence of Primary Refractory Anemia with Ringed Sideroblasts and T Cell-Lymphoblastic Non-Hodgkin Lymphoma

The co-existence of de novo myelodysplastic syndrome (MDS) and non-Hodgkin lymphoma (NHL) prior to therapy is an extremely unusual finding. We report here a case of co-existent de novo MDS-refractory cytopenia with multilineage dysplasia and T-cell NHL, including clinical features, histopathological findings, molecular assessment, treatment course and outcomes. Other cases from the literature showing co-existence of both disorders are also reviewed; to date 19 similar cases have been reported. Among all cases (including the present patient), eight cases were diagnosed with de novo MDS and NHL simultaneously, which were considered to be true coincidences. The mechanisms responsible for the appearance of co-existence have not yet been ascertained, however in the present case a common chromosomal abnormality (20q deletion) was found in bone marrow and lymph node preparations. We conclude, therefore, that the co-existent de novo MDS and T-cell NHL seen in the present case may have a common origin.

show abstract

T-cell Non-Hodgkin lymphoma associated with myelodysplasia: A case report in a child

Reis

Bahadır

Erduran

2018

Medical Science and Discovery

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Coexistence of Primary Refractory Anemia with Ringed Sideroblasts and T Cell-Lymphoblastic Non-Hodgkin Lymphoma

Cited by 3 publications

References 6 publications

Two cases of concomitant diffuse large B‐cell lymphoma and myelodysplastic syndrome

Two cases of concomitant diffuse large B‐cell lymphoma and myelodysplastic syndrome

Co-Existent de novo Myelodysplastic Syndrome and T-cell Non-Hodgkin Lymphoma: a Common Origin or Not?

T-cell Non-Hodgkin lymphoma associated with myelodysplasia: A case report in a child

Contact Info

Product

Resources

About