Coexistence of Meyerson’s with Sutton’s Naevus after Sunburn

Abstract

We describe the simultaneous occurrence of perinaevic eczema (Meyerson’s naevi) and Sutton’s halo naevus in one patient. Characteristic clinical and histological features of perinaevic eczema were found around four benign melanocytic naevi on the limbs. In addition, the patient had a typical Sutton’s naevus on the back. The association of Meyerson’s naevi and Sutton’s naevus has been reported only once in the past literature. Both diseases appeared a few weeks after a severe sunburn. The role of sun exposure in the development of eczematiform and/or vitiligoid reactions around melanocytic naevi is discussed.

Halo dermatitis followed by the development of vitiligo associated with Sutton's nevi

“…24 Hence, UV radiation seems to be able to induce the development of halo dermatitis lesions. This assumption is supported by a report by Petit et al, 10 who describe the case of a patient who developed several halo dermatitis lesions and one Sutton's nevus a few weeks after experiencing a severe sunburn. Also, other factors than UV radiation seem to be able to trigger the formation of corresponding lesions.…”

“…This is composed of mainly CD4 1 lymphocytes and sometimes eosinophils and mastcells. 10,15,16 The pigmented lesion in the center never shows regression and the nevus always persists after the surrounding inflammation has resolved. This is in sharp contrast to the clinical course of the widespread Sutton's nevi.…”

Dermoscopy, Reflectance Confocal Microscopy and Immunohistochemical Analysis in Melanocytic Lesions with Meyerson's Phenomenon

“…Meyerson's phenomenon can be confined to one, some or all nevi in a given patient. It was also described in association with some nonmelanocytic lesions, including seborrheic keratosis, histiocytofibroma, basal cell carcinoma, squamous cell carcinoma, sebaceous nevus, vascular malformations, insect bites, keloids and molluscum contagiosum [12,13,14,15]. Meyerson's nevi are more common in adult males, typically arising on the trunk and proximal extremities [1].…”

“…The nevi usually persist unchanged once the regression of the eczema occurs, but progression to halo nevi was also rarely documented. Coexistence of Meyerson's nevi and halo nevi was also seen in rare cases [16,17]. An association with atopy has been reported, but its etiopathogenesis remains unknown.…”

Progression of Meyerson’s Naevus to Sutton’s Naevus

“…Melanocytic naevi can suffer two types of perilesional inflammation, a depigmentation and a dermatitis [1, 2]. The former seems to be a form of cell-mediated, auto-immune reaction directed towards the destruction of the naevus and related to vitiligo.…”