Coexistence of Left Main and Right Coronary Artery Ostial Stenosis: Demographic and Angiographic Features

Abstract

This study was designed to evaluate ostial left main coronary artery (LMCA) stenosis and investigate concomitant stenotic lesions of LMCA and right coronary arteries (RCA) and their demographic and angiographic features. We evaluated 11,283 patients who underwent coronary angiography. Patients were placed into four groups according to having ostial or nonostial LMCA or RCA stenosis. Significant LMCA stenosis was observed in 242 (8.3%) of the patients, and only 68 (28.1%) of them had significant ostial LMCA stenosis. There was a significant correlation between ostial stenosis of LMCA and RCA (p ¼ 0.03). The frequency of female gender was greater in ostial LMCA and ostial RCA stenosis groups compared with the other groups (p ¼ 0.01). Ostial LMCA and RCA stenosis were related significantly. Both female predominance and coexistence of ostial LMCA and RCA stenosis might have suggest a different pathological ground for this disease.

Incidence, predictors, clinical profile, management and outcome of patients with isolated left main coronary artery ostial disease

“…Left anterior oblique, right anterior oblique and anterior caudal views were recorded in every patient. Ostial lesion was defined as a proximally significant stenosis up to 3 mm from the coronary origin 9 . Non-ostial lesion was defined as significant stenosis distal to 3 mm from the coronary origin 9 .…”

“…Ostial lesion was defined as a proximally significant stenosis up to 3 mm from the coronary origin 9 . Non-ostial lesion was defined as significant stenosis distal to 3 mm from the coronary origin 9 . Any subtle change in pressure waveform as the catheter engaged the ostium of LMCA was carefully noted.…”

“…The incidence of isolated coronary ostial stenosis has varied between 0.13% and 2.7% 8, 9. In the majority of cases there is coexisting disease in multiple coronary vessels.…”

Left Main Coronary Artery Disease and Outcomes after Percutaneous Coronary Intervention for Chronic Total Occlusions

“…However, the exclusive role in blood supply for the left ventricle and the characteristic histology of the LMCA (lack of adventitia and the substantial smooth muscle and elastic tissue) makes the LMCA unique among all coronary arteries [14]. Therefore, to truly define the predictive role of LMCA disease, we included not only well-established clinical risk factors for cardiovascular mortality, but also variables that depict the atherosclerotic burden and lesions complexity of those patients into our Cox proportional hazard models to adjust the risk.…”

Outcomes After Percutaneous Coronary Intervention in Women: Are There Differences When Compared with Men?

“…[58] Women may be more likely than men to have disease at the ostium of the LMS. [59] Studies have shown that PCI for ostial LMS disease has a low rate of MACE not significantly different to the results after CABG. [60]…”