Coexistence of Diffuse Idiopathic Skeletal Hyperostosis and Ankylosing Spondylitis: A Case Report

Abstract

Diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis are two diseases which are listed in the differential diagnosis of each other. There have been limited numbers of case reports regarding the coexistence of both diseases in the literature. We describe a patient who demonstrated the features of diffuse idiopathic skeletal hyperostosis with coexisting features resembling ankylosing spondylitis in order to discuss the association of the two diseases.

Diffuse idiopathic skeletal hyperostosis: Differentiation from ankylosing spondylitis

“…So far, only 16 patients with the coexistence of the two diseases have been reported in the English literature [51][52][53][54][55][56][57][58][59][60][61][62]. The radiologic fi ndings of axial involvement of AS and DISH are so different that, in patients with this coexistence, it is possible for experts to recognize changes caused by each of the two diseases at any level.…”

Not so Mutually Exclusive Diseases: A Case of Co-occurrence of Inflammatory Spondyloarthritis and Diffuse Skeletal Hyperostosis in a Young Patient

“…Even though SpA and DISH have different clinical expressions and characteristic radiological patterns, this case report highlights the exceptional coexistence of abnormalities suggestive of both conditions in the same patient [2,7] . Only few case reports regarding the simultaneous occurrence of both diseases are described in the medical literature.…”

“…Even though SpA and DISH have different clinical expressions and characteristic radiological patterns, this case report highlights the exceptional coexistence of abnormalities suggestive of both conditions in the same patient [ 2 , 7 ] .…”

A probable case of diffuse idiopathic skeletal hyperostosis from an early modern crypt in Eastern Germany

“…The “candlewax”‐like ossification of the anterior longitudinal ligament is the main characteristics of DISH and typically occurs on the right side of the thoracic vertebrae because of the overlying aorta on the left side (Roberts & Manchester, 2010). This anterolateral, flowing ossification does not affect the intervertebral space, and the absence of changes in the sacroiliac joint is diagnostic criteria for DISH (Kozanoglu, Guzel, Guler‐Uysal, & Goncu, 2002). Enthesophytes are commonly but not exclusively associated with DISH, for example, at the iliac crest, and should only be an additional criterium (Van der Merwe, Maat, & Watt, 2012).…”