2023
DOI: 10.1103/physrevlett.131.138101
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Coexistence of Crumpling and Flat Sheet Conformations in Two-Dimensional Polymer Networks: An Understanding of Aggrecan Self-Assembly

Alexandros Chremos,
Ferenc Horkay
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Cited by 2 publications
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“…The most abundant proteoglycan in cartilage is the highly charged bottlebrush shaped molecule aggrecan. 4–7 It is composed of an extended protein core (approximate length 3000 Å) to which are attached about a hundred glucosaminoglycan (GAG) chains (chondroitin sulfate and keratin sulfate blocks) of length 200–500 Å. These act as bristles oriented randomly around the protein core, at intervals of 20–50 Å along its length.…”
Section: Introductionmentioning
confidence: 99%
“…The most abundant proteoglycan in cartilage is the highly charged bottlebrush shaped molecule aggrecan. 4–7 It is composed of an extended protein core (approximate length 3000 Å) to which are attached about a hundred glucosaminoglycan (GAG) chains (chondroitin sulfate and keratin sulfate blocks) of length 200–500 Å. These act as bristles oriented randomly around the protein core, at intervals of 20–50 Å along its length.…”
Section: Introductionmentioning
confidence: 99%