Coeliac disease in Europe

McLoughlin, Ramona; Sebastian, Shaji; Qasim, Asghar; McNamara, Deirdre; O'Connor, H.J.; Buckley, Martin; O’Moráin, Colm

doi:10.1046/j.1365-2036.18.s3.1.x

Cited by 23 publications

(11 citation statements)

References 11 publications

(8 reference statements)

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“…A further 20 studies attempted specifically to cost GI conditions: IBD, 737 738 IBS, 739-741 GI cancer, 324 upper gastrointestinal disease (UGI), 697 742-744 traveller's diarrhoea, 653 non-specific abdominal pain, 745 colic, 746 GERD, 16 and dyspepsia. 747 748 A further paper examined the economic consequences of waiting time for gallbladder surgery.…”

Section: Economic Burden Of Gi Diseasementioning

confidence: 99%

Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: a review of the evidence

Roberts

Ali

Cheung

et al. 2007

Gut

137

106

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Section: Economic Burden Of Gi Diseasementioning

confidence: 99%

Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: a review of the evidence

Roberts

Ali

Cheung

et al. 2007

Gut

137

106

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“…Epidemiological studies have shown that the prevalence of CD is in a range between 1/100 and 1/150 in both Europe and the USA. The prevalence of CD is increased in first-degree relatives of individuals with biopsy-proven CD (4-12%) [1] ( table 1 ).…”

Section: Prevalence and Pathogenesis Of CDmentioning

confidence: 99%

Celiac Disease: What’s New about It?

Gasbarrini

Malandrino²,

Giorgio³

et al. 2008

Dig Dis

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In the present review we will try to summarize the clinical and diagnostic features of celiac disease (CD) as well as the new findings on extraintestinal manifestation. CD is an immune-mediated enteropathy caused by a permanent gluten intolerance. In the last years, the diagnosis is becoming more and more frequent because of the recognition of ‘new’ symptoms and associated extraintestinal manifestations. Classical CD is dominated by symptoms and sequelae of gastrointestinal malabsorption. In the ‘atypical forms’, the extraintestinal features usually predominate, with few or no gastrointestinal symptoms. Silent CD refers to asymptomatic patients with a positive serologic test and villous atrophy on biopsy. This form is detected by screening of high-risk individuals, or villous atrophy occasionally may be detected by endoscopy and biopsy conducted for another reason. The potential form is diagnosed in groups at risk including relatives of celiac patients, Down syndrome and autoimmune diseases. Latent CD is defined by positive serological tests but not histological changes on biopsy. These individuals are asymptomatic, but later may develop symptoms and/or histological alterations. Recognition of atypical manifestations of CD is very important because many cases can remain undiagnosed with an increased risk of long-term complications.

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“…Как видно из таблицы [17], распространенность целиакии в некоторых странах может достигать 1:200 [18,19] и даже 1:100 [20].…”

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“…У таких больных в клинической сим-птоматике преобладают не симптомы мальабсор-бции и диареи, а внекишечные манифестации, такие как железодефицитная анемия, афтоз-ный стоматит, дерматит Дюринга, остеопороз, маленький рост, задержка полового развития, Распространенность целиакии в Европе [17] …”

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