Stroke is a prevalent issue within the community as the diagnosis of stroke plays an essential role in the Quality of life (QoL) of the patient. This study is a Systematic Literature Review (SLR) of QoL of stroke patients according to the statement of Preferred Reporting Items for Systematic Review (PRISMA). A published article between 2008 to 2020 from four databases namely EBSCO Medline, Ovid, PubMed and Science Direct were included in the study. After the identification and screening process, 37 articles were reviewed thoroughly in the study. Analysis of these 37 articles revealed the QoL of stroke patients is poor compared to the general population. The diagnosis of stroke impacted both physical and mental dimension of QoL in which the most impacted domain was reported to be the physical domain. Among the influential factors towards QoL were age, patient’s disability, gender, patient’s comorbidity, income status and family support. To improve the QoL of the patients, it’s highly imperative to consider the factors influencing QoL in the treatment plan of the patients.