Çocuklarda akut zehirlenme; 2015 yılında Marmara Üniversitesi Hastanesi’ne başvuran olguların değerlendirilmesi

Abstract

Objectives: According to Turkish Statistical Institute (TurkStat), 6477 children aged between 1 and 17 years, died in 2015 and 29.5% (n=1909) of these deaths were because of injuries due to external causes and poisoning. Our aim is to produce solutions to this problem by evaluating demographics, clinical features of patients and the causes and consequences of poisoning. Materials and Methods: The hospital medical records of children who were admitted with acute intoxication to Pediatric Emergency Service at Marmara University Hospital in 2015, were evaluated retrospectively. Results: In 2015, a total of 1110 patients applied to the hospital due to poisoning. Of these cases, 31.6% (n = 351) were children, about half of them were male (n = 173) and half were female (n = 178). The mean age of males was 6.24 years and mean age of females was 8.47 years. Sixty percent (n=213) of patients were in 0-6 age group, 8% (n=28) of patients were in 7-11 age group, 32 % (n=110) of patients were in 12-18 age group. Forty-six point one percent (n = 162) were poisoned with medications. Among the pharmaceuticals, paracetamol was the most commonly used agent (14.8%). In non-pharmaceuticals, caustic/corrosive substances (detergent, bleach, acetone etc.) were the most frequently used agents (54%). Conclusion: In this study, 80.3% of the cases were preventable accidental poisoning. Regulations on child-resistant packaging should come into force as soon as possible.

Poisonings in childhood: A 5-year experience of a tertiary city hospital in İstanbul

“…2,17,23,24 In our study, the most common cause of non-pharmaceutical poisoning was corrosivecaustic substances, in line with the recent studies conducted in Turkey. 3,25 In the second place, poisoning with detergents came forth. Esophageal injury should be considered after poisoning with corrosive-caustic substances.…”

Amitriptyline Intoxication in Children

“…One of the most common sources of intoxication, after multiple drug intake and corrosive poisoning, is tricyclic antidepressants (TCAs). [2][3][4][5] Methods commonly used by adolescents for purposes of suicide include hanging, exhaust fume inhalation, and medication overdoses including acetaminophen, benzodiazepines, and TCAs. [6][7][8] Intoxications caused by the TCA amitriptyline are very important because of their adverse effects and potentially fatal outcomes.…”

“…Epidemiological studies from Turkey have reported that children constitute one-third of patients admitted to the emergency department due to poisoning and that more than half of these are children younger than 6 years with accidental intoxications. One of the most common sources of intoxication, after multiple drug intake and corrosive poisoning, is tricyclic antidepressants (TCAs) 2–5 …”