Cochrane corner: adenosine versus intravenous calcium channel antagonists for supraventricular tachycardia

Abstract

Article:Alabed, S. orcid.org/0000-0002-9960-7587, Providência, R. and Chico, T.J.A. orcid.org/0000-0002-7458-5481 (2018) Cochrane corner: adenosine versus intravenous calcium channel antagonists for supraventricular tachycardia. Heart.

Unmasking Adenosine: The Purinergic Signalling Molecule Critical to Arrhythmia Pathophysiology and Management

“…However, when used appropriately in SVT, CCAs are as clinically effective as adenosine. 51 The time to cardioversion with CCAs is slightly longer and the risk of hypotension is slightly greater, although the latter is rare and is mitigated by slower infusions. 42 The rates of minor side-effects were higher with adenosine.…”

Good Things Come To Those Who Wait? Adenosine Administration versus a Waiting Period after Cavo-Tricuspid Isthmus Radiofrequency Ablation.

“…Despite very widespread use in an emergency-room setting for the acute management of supraventricular tachycardia, there are very few reports of significant adverse effects and none in a meta-analysis of randomised trials. 15 Unfortunately it produces unpleasant chest tightness in most patients, tolerable as a single experience but increasingly unpleasant with repetition. This makes a single bolus preferable to a regime of escalating doses.…”