Cochlear Microcirculation: Effect of Adrenergic Agonists on Arteriole Diameter

Carrasco, Vincent N.; Prazma, Jiri; Faber, James E.; Triana, Rudolph J.; Pillsbury, Harold C.

doi:10.1001/archotol.1990.01870040033009

Cited by 47 publications

(30 citation statements)

References 14 publications

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“…Some studies justify that the sensorineural hearing loss that happens with aging is related to a microcirculatory DBP diastolic blood pressure, SBP systolic blood pressure insufficiency that occurs due to vascular occlusion caused by emboli, hemorrhage or vasospasm, and these happen because of a syndrome of hyperviscosity or microangiopathy caused by diabetes or hypertension, and the latter could, through histopathological mechanisms cause the sensorineural hearing loss [15,16]. As to gender, there was a difference in the men to women ratio in both groups, due to the fact that we did not pair the sample-cases were taken at random, during regular medical visits.…”

Section: Discussionmentioning

confidence: 99%

Effects of Hypertension on Hearing

Agarwal

Mishra

Jagade

et al. 2013

Indian J Otolaryngol Head Neck Surg

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To determine the likely association between hypertension and hearing loss. 150 cases and 124 controls, both genders, aged 45-64, included in the research after sample estimation. Hypertension was verified through blood pressure readings and was classified as grade 1, grade 2 and grade 3 hypertension or no hypertension according to the blood pressure readings. Hearing was assessed by measuring pure tone threshold at various frequencies ranging between 250 and 8,000 Hz. There is a significant association between hypertension and increase in the hearing threshold. Hearing loss in the population under study suggests that hypertension is an accelerating factor of degeneration of the hearing apparatus due to aging. Association between Increased hearing threshold and hypertension in this research, can allow for an integrated work of cardiologists, nephrologists, otorhinolaryngologists, audiologists and other health professionals concerned with alterations caused by hypertension.

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Section: Discussionmentioning

confidence: 99%

Effects of Hypertension on Hearing

Agarwal

Mishra

Jagade

et al. 2013

Indian J Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

“…Some studies justify that the sensorineural hearing loss that happens with aging is related to a microcirculatory insufficiency that occurs due to vascular occlusion caused by emboli, hemorrhage or vasospasm, and these happen because of a syndrome of hyperviscosity or microangiopathy caused by diabetes or hypertension, and the latter could, through histopathological mechanisms cause the sensorineural hearing loss 28,29 .…”

Section: Discussionmentioning

confidence: 99%

Hipertensão como fator associado à perda auditiva

Marchiori

Filho

Matsuo

2006

Rev. Bras. Otorrinolaringol.

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Aim: To identify likely association between blood hypertension and hearing loss. Design: A non-paired casecontrol study. Setting: Institutional work carried out at Universidade Norte do Paraná, in South Brazil. Material and Method: 154 cases and 154 controls, both genders, aged 45 to 64, included in the research after sample estimation. Methodology: Hypertension was verified through blood pressure readings and by a systematized questionnaire about hypertension and the use of medication for blood pressure. Hearing was assessed through tonal threshold audiometrics and audiologic anamneses. Non-conditional logistic regression was used in order to control likely confusion or modification of effect of other variables on interest associations. Results: There is a significant association between blood hypertension and hearing loss. Hearing loss in the population under study suggests that hypertension is an accelerating factor of degeneration of the hearing apparatus due to aging. Conclusions: The results in this research, through evidence of association between blood hypertension and hearing loss, can allow for an integrated work of cardiologists, nephrologists, otorhinolaryngologists, audiologists and other health professionals concerned with alterations caused by blood hypertension.

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“…58,59 It is possible that hypertension could, through such factors, cause hearing impairment, and consequently, it would be expected that workers exposed to high noise levels and having hypertension would be more prone to hearing impairment and hearing loss. 59 The occurrence of hearing impairment in our exposed population was not associated with hypertension. There was no statistically significant difference between hypertensive and normotensive exposed workers regarding their mean hearing threshold and NIHL.…”

mentioning

confidence: 99%

Angiotensin-converting enzyme gene polymorphisms and hypertension in occupational noise exposure in Egypt

Zawilla

Shaker

Abdelaal

et al. 2014

International Journal of Occupational and Environmental Health

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Background: The gene-environment interaction in the pathogenesis of hypertension has not been extensively studied in occupational noise. Objectives: The aim of this study was to determine the relationship between noise and hypertension in Egyptian workers, the interaction of angiotensin-converting enzyme (ACE) gene polymorphisms as modifiers, and the possible relationship between noise hearing impairment and hypertension. Methods: Study subjects were divided into two groups depending on noise exposure level. The control group (n5161) was exposed to noise intensity ,85 dB and the exposed group (n5217) was exposed to noise intensity §85 dB. A polymerase chain reaction was used to differentiate the various genotypes of ACE insertion/deletion (I/D) and ACE G2350A. Results: Noise significantly increased the likelihood of hypertension. Carriers of the genotypes AG, GG, and DD were vulnerable to hypertension on noise exposure. No association between hypertension and hearing impairment or noise-induced hearing loss (NIHL) was found. Conclusion: Our results support the association between ACE gene polymorphisms and occurrence of hypertension in noise-exposed workers.

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Cochlear Microcirculation: Effect of Adrenergic Agonists on Arteriole Diameter

Cited by 47 publications

References 14 publications

Effects of Hypertension on Hearing

Effects of Hypertension on Hearing

Hipertensão como fator associado à perda auditiva

Angiotensin-converting enzyme gene polymorphisms and hypertension in occupational noise exposure in Egypt

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