“…Previously, the effects of acute energy failure on the cochlea have been studied using anoxia or chemical asphyxiants such as carbon monoxide, cyanide and nitric oxide [Brown et al, 1983;Kong et al, 1996;Nuttall and Lawrence, 1979;Pai et al, 1998;Rao and Fechter, 2000;Ruan et al, 1997;Tawackoli et al, 2001;Thalmann et al, 1977]. In these studies, electrophysiological methods were primarily used to investigate the pathophysiology of cochlear dysfunction, and only a small number of morphological studies limited to the organ of Corti and spiral ganglion cells have been conducted [Kong et al, 1996;Pai et al, 1998;Ruan et al, 1997].…”