Coccidioidomycosis in India: report of a second imported case

Verghese, S.; Arjundas, D.; Krishnakumar, K. C.; Padmaja, P.; Elizabeth, D.; Padhye, A. A.; Warnock, D. W.

doi:10.1080/714031103

Cited by 7 publications

(10 citation statements)

References 4 publications

(7 reference statements)

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“…With the ease of global travel, imported cases of coccidioidomycosis have been reported in travellers from Europe, Canada and Asian countries including India. 3–7 Our patient, a resident of Delhi, India, had a history of travel to Phoenix (Arizona) and Nevada. He was immunocompetent and possibly acquired the infection during his travels.…”

Section: Discussionmentioning

confidence: 99%

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Coccidioidomycosis masquerading as skeletal tuberculosis: an imported case and review of coccidioidomycosis in India

et al. 2013

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We describe a possible imported case of osteo-articular coccidioidomycosis in India. Culture of the computed tomography-guided aspirate revealed the growth of Coccidioides spp., which was identified as Coccidioides posadasii by sequencing of the internal transcribed spacer (ITS) region of rDNA. He was successfully treated with amphotericin B followed by itraconazole. All the previous published reports of coccidioidomycosis cases diagnosed in India are also reviewed in order to increase the awareness of this disease in non-endemic areas.

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Section: Discussionmentioning

confidence: 99%

“…Only five imported cases of coccidioidomycosis have been reported. [3][4][5][6][7] Our case is the sixth in the series and was diagnosed late due to a lack of awareness of this disease. We review all reported cases from India.…”

Section: Introductionmentioning

confidence: 99%

Coccidioidomycosis masquerading as skeletal tuberculosis: an imported case and review of coccidioidomycosis in India

et al. 2013

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“…Frequent transregional and transnational population movements have been associated with an increasing number of cases of CM in previously non‐endemic regions. Two patients with CM were recently identified in India, 3,4 and nearly 40 patients have been identified in Japan 5 . Although China is not a known endemic area for CM, the number of case reports of CM has been increasing.…”

Section: Discussionmentioning

confidence: 99%

Primary pulmonary coccidioidomycosis in China

et al. 2010

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Coccidioidomycosis is a fungal infection endemic to south-west USA, north Mexico and parts of Central and South America. We report here a case of primary pulmonary coccidioidomycosis in a previously healthy 14-year-old boy in China, which is considered a non-endemic country. The patient had non-specific symptoms of pulmonary infection, including fever, non-productive cough and night sweats. Both spherules and endospores of Coccidioides immitis were seen histologically following transbronchial biopsy of a cavitary lesion. The patient was treated with amphotericin B and fluconazole. Follow up 6 months post discharge found that the patient made a good recovery.

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“…In Canada, a high number of reported cases in Ontario have even prompted reviews that investigate the impact of fungi on the city [84]. Outside of the western hemisphere, coccidioidomycosis has been observed in recent travelers of endemic zones returning home to Europe [85][86][87], Australia [88][89][90], and Asia [91][92][93][94]. The threat of coccidioidomycosis is thus a very important consideration for traveling individuals with a propensity for coccidioidal infection, such as immunocompromised individuals.…”

Section: Risk Factors For the Acquisition Of Coccidioidomycosismentioning

confidence: 99%

Coccidioidomycosis: Epidemiology, Fungal Pathogenesis, and Therapeutic Development

2019

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Purpose of Review Coccidioidomycosis can result from the inhalation of infectious spores of Coccidioides species (spp.) immitis or posadasii. Clinical manifestations range from mild flu-like disease to severe disseminated infection that can require life-long therapy. Burden of this mycosis is high in the southwest region of the USA where it is well characterized, and in many areas of Mexico and Latin America where it is inadequately characterized. Here, we provide historical data and current knowledge on Coccidioides spp. pathogenesis as well as recent progress in therapeutic and vaccine development against coccidioidomycosis. Recent Findings The virulence mechanisms of Coccidioides spp. are largely unknown; however, production and regulation of a spherule glycoprotein, ammonium production, and melanization have all been proposed as integral factors in Coccidioides spp.' pathogenesis. Therapeutic options are limited and not 100% effective, but individualized treatment with triazoles or amphotericin B over the course of pulmonary or disseminated infection can be effective in resolution of coccidioidomycosis. Human immunization has not been achieved but efforts are ongoing. Summary Advances in therapeutic and vaccine development are imperative for the prevention and treatment of coccidioidomycosis, especially for those individuals at risk either living or traveling to or from endemic areas.

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Coccidioidomycosis in India: report of a second imported case

Cited by 7 publications

References 4 publications

Coccidioidomycosis masquerading as skeletal tuberculosis: an imported case and review of coccidioidomycosis in India

Coccidioidomycosis masquerading as skeletal tuberculosis: an imported case and review of coccidioidomycosis in India

Primary pulmonary coccidioidomycosis in China

Coccidioidomycosis: Epidemiology, Fungal Pathogenesis, and Therapeutic Development

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