“…The development of public health programs aimed at problematic cocaine users is challenged by the fact that they can have complex patterns of drug use, particularly with respect to polysubstance use and routes of drug administration (Fischer et al, 2010;Guindalini, Vallada, Breen, & Laranjeira, 2006;Latkin, Knowlton, & Sherman, 2001;Prinzleve et al, 2004;Roy, Arruda, Vaillancourt, et al, 2012;Shaw, Shah, Jolly, & Wylie, 2008).…”