Cobalt(III)-Catalyzed Free-Amine-Directed Site-Selective Allylation in 2-Aminobiaryls with Vinyl Cyclopropanes

3-Halo-5,6-dihydro-4H-1,2-oxazine N-oxides as synthetic equivalents of unsaturated nitrile oxides in the [3 + 2]-cycloaddition with arynes: synthesis of substituted 3-vinyl-1,2-benzisoxazoles

“…mesityl nitrile oxide) (Scheme 1, (2)) 9 c or those generated in situ from the corresponding hydroximoyl chlorides (chlorooximes) (Scheme 1, (3)). 9,10 Consequently, it leads to some limitations in the product scope. For instance, α,β-unsaturated hydroximoyl chlorides are rarely exploited and are mostly limited to β-aryl-substituted derivatives.…”

Expedient C–H allylation of sulfoxonium ylides: merging C–H and C–C/C–het bond activation

“…5 Correspondingly, the formation of C–C and C–hetero bonds at the C(olefinic)–H of sulfoxonium ylides has been widely studied. 6 Despite this progress, C–H activation of weak chelation-assisted sulfoxonium ylides and ring-opening of strained vinyl carbo-/heterocycles 7 using less expensive Co-catalysis remains largely underexplored. The challenges include selectivity of C(olefinic)–H versus C(aryl)–H bond activation of the ylide as well as the compatibility of the sulfur atom in catalyst turnover.…”