Cobalt, copper, and chromium-catalyzed carbon-carbon coupling reactions using a broad spectrum of Grignard reagents as reaction partners

Abstract

The cobalt, copper and chromium catalyzed cross-coupling reaction of various Grignard reagents with electrophilic substrates is a powerful technique for the construction of carbon-carbon bonds, enabling the preparation of a wide variety of organic compounds that are employed in the pharmaceutical industry, as agricultural compounds, and for forming organic electronic materials. This review highlights major developments in carbon-carbon cross-coupling reactions catalyzed by cobalt, copper and chromium complexes over the past decade.